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Gene Review

NAS6  -  Nas6p

Saccharomyces cerevisiae S288c

Synonyms: G8564, Proteasome non-ATPase subunit 6, YGR232W
 
 
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Disease relevance of NAS6

  • However, the NAS7, but not NAS6, disruptant cells caused high sensitivity to heat stress, being unable to proliferate at 37 degreesC [1].
 

High impact information on NAS6

  • Disruption of these yeast genes, NAS6 and NAS7, had no effect on cell viability, indicating that neither of the two subunits is essential for proliferation of yeast cells [1].
 

Analytical, diagnostic and therapeutic context of NAS6

  • Purification, crystallization and preliminary X-ray diffraction analysis of yeast regulatory particle non-ATPase subunit 6 (Nas6p) [2].

References

  1. cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome. Hori, T., Kato, S., Saeki, M., DeMartino, G.N., Slaughter, C.A., Takeuchi, J., Toh-e, A., Tanaka, K. Gene (1998) [Pubmed]
  2. Purification, crystallization and preliminary X-ray diffraction analysis of yeast regulatory particle non-ATPase subunit 6 (Nas6p). Adachi, N., Padmanabhan, B., Kataoka, K., Kijima, K., Yamaki, M., Horikoshi, M. Acta Crystallogr. D Biol. Crystallogr. (2002) [Pubmed]
 
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