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Gene Review

RPS5  -  ribosomal 40S subunit protein S5

Saccharomyces cerevisiae S288c

Synonyms: 40S ribosomal protein S5, J2045, RP14, RPS2, S2, ...
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High impact information on RPS5

  • Surprisingly, the RPS5 core promoter can be activated by various activation domains fused to a GAL4 DNA binding domain, but not by the original upstream activating sequence (UAS) of the RPS5 gene [1].
  • Requirement for yeast TAF145 function in transcriptional activation of the RPS5 promoter that depends on both core promoter structure and upstream activating sequences [1].
  • Here, we show in these mutants that the transcription of the RPS5 gene is impaired, mostly due to a defect in transcriptional activation rather than to a defect in core promoter recognition, although the latter is slightly affected as well [1].
  • We also show that RPS5 acts on the SUC1 and SUC4 genes but not on SUC2 and SUC3, which are members of the SUC family [2].
  • Phenotype traits associated with different alleles at the RPS5 locus in Saccharomyces cerevisiae [2].

Biological context of RPS5

  • We suggest that genes similar RPS5 are responsible for the low levels of invertase activity observed in diploid strains of S. cerevisiae [3].


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