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RPL40B  -  ubiquitin-ribosomal 60S subunit protein...

Saccharomyces cerevisiae S288c

Synonyms: CEP52B, UB12, UBI2
 
 
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High impact information on RPL40B

  • UB11, UB12 and UB13 encode hybrid proteins in which ubiquitin is fused to unrelated ('tail') amino acid sequences [1].
  • UB11 and UB12 encode identical 52-residue tails, whereas UB13 encodes a different 76-residue tail [1].
  • PTR2 was tightly linked to the UBI2 gene, with the coding sequences being separated by a 466-bp region and oriented so that the genes were transcribed convergently [2].
  • The complete sequence of a 15,820 bp segment of Saccharomyces cerevisiae chromosome XI contains the UBI2 and MPL1 genes and three new open reading frames [3].
 

Analytical, diagnostic and therapeutic context of RPL40B

  • It contains four open reading frames (ORFs) which encode potential proteins of more than 100 amino acid residues, as well as the UBI2 gene which carries an intron and does not show up as an ORF in the sequence analysis programs [3].

References

  1. The yeast ubiquitin genes: a family of natural gene fusions. Ozkaynak, E., Finley, D., Solomon, M.J., Varshavsky, A. EMBO J. (1987) [Pubmed]
  2. Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene. Perry, J.R., Basrai, M.A., Steiner, H.Y., Naider, F., Becker, J.M. Mol. Cell. Biol. (1994) [Pubmed]
  3. The complete sequence of a 15,820 bp segment of Saccharomyces cerevisiae chromosome XI contains the UBI2 and MPL1 genes and three new open reading frames. Bou, G., Esteban, P.F., Baladron, V., Gonzalez, G.A., Cantalejo, J.G., Remacha, M., Jimenez, A., Del Rey, F., Ballesta, J.P., Revuelta, J.L. Yeast (1993) [Pubmed]
 
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