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Gene Review

RPS19A  -  ribosomal 40S subunit protein S19A

Saccharomyces cerevisiae S288c

Synonyms: 40S ribosomal protein S19-A, RP55A, RPS16AA, S16a, YOL121C, ...
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High impact information on RPS19A

  • The genes encoding yeast ribosomal proteins rp28 and S16A are linked and occur duplicated in the yeast genome [1].
  • The isolated proteins are YP 6, YP 7, YP 9, YP 12, YP 14', YP 14'', YP 28, YP 38, YP 45, YP 50, YP 52, YP 58, YP 63, and YP 70 [2].
  • Comparison of the amino acid sequences of these proteins with ribosomal protein sequences of other organisms revealed that halobacterial protein S12 has homology with the eukaryotic protein S16A from Saccharomyces cerevisiae, while S15 is significantly related to the Xenopus laevis S19 protein [3].
  • NO422 and NO425 correspond to the split ribosomal protein genes encoding S16A and rp28, respectively, NO450 displays a striking similarity with serine/threonine protein kinase genes, in particular with STE20, and therefore may encode a novel member of this protein family [4].


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