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Gene Review

SYG1  -  Syg1p

Saccharomyces cerevisiae S288c

Synonyms: Protein SYG1, YIL047C
 
 
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Disease relevance of SYG1

 

High impact information on SYG1

  • Consistent with these genetic observations, the suppressing form of Syg1p can interact with the STE4 gene product, as determined by a two-hybrid assay [2].
  • Deletion mutants of SYG1 indicate that complete gpa1 suppression requires removal of all of these hydrophobic regions [2].
  • Interestingly, this truncated protein localizes to the same plasma membrane-enriched subcellular fraction as does full-length Syg1p [2].
 

Biological context of SYG1

  • One deletion mutant (SYG1 delta 340) can suppress the cell cycle arrest associated with gpa1, but the cells retain a differentiated morphology [2].

References

  1. Identification and characterization of the Arabidopsis PHO1 gene involved in phosphate loading to the xylem. Hamburger, D., Rezzonico, E., MacDonald-Comber Petétot, J., Somerville, C., Poirier, Y. Plant Cell (2002) [Pubmed]
  2. Truncated forms of a novel yeast protein suppress the lethality of a G protein alpha subunit deficiency by interacting with the beta subunit. Spain, B.H., Koo, D., Ramakrishnan, M., Dzudzor, B., Colicelli, J. J. Biol. Chem. (1995) [Pubmed]
 
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