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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SGN1  -  Sgn1p

Saccharomyces cerevisiae S288c

Synonyms: RBP1, RBP29, RNA-binding protein SGN1, YIB1C, YIR001C
 
 
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High impact information on SGN1

  • A system to study transcription by yeast RNA polymerase I within the chromosomal context: functional analysis of the ribosomal DNA enhancer and the RBP1/REB1 binding sites [1].
  • We also applied the system to study the function of the rDNA binding protein RBP1/REB1 [1].
  • Rbp29p can be co-immunoprecipitated with the poly(A) tail-binding protein Pab1p from crude yeast extracts in a dosage- and RNA-dependent manner [2].
  • Although RBP29 is not essential for cell viability, its deletion exacerbates the slow growth phenotype of yeast strains harboring mutations in the eIF4G genes TIF4631 and TIF4632 [2].

References

  1. A system to study transcription by yeast RNA polymerase I within the chromosomal context: functional analysis of the ribosomal DNA enhancer and the RBP1/REB1 binding sites. Kulkens, T., van der Sande, C.A., Dekker, A.F., van Heerikhuizen, H., Planta, R.J. EMBO J. (1992) [Pubmed]
  2. The Saccharomyces cerevisiae RNA-binding protein Rbp29 functions in cytoplasmic mRNA metabolism. Winstall, E., Sadowski, M., Kuhn, U., Wahle, E., Sachs, A.B. J. Biol. Chem. (2000) [Pubmed]
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