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Gene Review

IBD2  -  Ibd2p

Saccharomyces cerevisiae S288c

Synonyms: Inhibition of bud division protein 2, N1714, Protein IBD2, YNL164C
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High impact information on IBD2

  • IBD2 encodes a novel component of the Bub2p-dependent spindle checkpoint in the budding yeast Saccharomyces cerevisiae [1].
  • In addition, overexpression of Mps1p caused partial mitotic arrest in ibd2Delta as well as in bub2Delta, suggesting that IBD2 encodes a novel component of the spindle checkpoint downstream of MPS1 [1].
  • We have isolated a novel Bfa1p interacting protein named Ibd2p in the budding yeast Saccharomyces cerevisiae [1].
  • Pds1p was also stabilized by the overexpression of Ibd2p in wild-type cells [1].
  • We found that IBD2 (Inhibition of Bud Division 2) is not an essential gene but its deletion mutant proceeded through the cell cycle in the presence of microtubule-destabilizing drugs, thereby inducing a sharp decrease in viability [1].


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