Gene Review:
PDS1 - Pds1p
Saccharomyces cerevisiae S288c
Synonyms:
Securin, YD9727.08C, YDR113C
- How do so few control so many? Nasmyth, K. Cell (2005)
- The yeast APC/C subunit Mnd2 prevents premature sister chromatid separation triggered by the meiosis-specific APC/C-Ama1. Oelschlaegel, T., Schwickart, M., Matos, J., Bogdanova, A., Camasses, A., Havlis, J., Shevchenko, A., Zachariae, W. Cell (2005)
- Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast. Alexandru, G., Uhlmann, F., Mechtler, K., Poupart, M.A., Nasmyth, K. Cell (2001)
- An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Ciosk, R., Zachariae, W., Michaelis, C., Shevchenko, A., Mann, M., Nasmyth, K. Cell (1998)
- Smt3/SUMO and Ubc9 are required for efficient APC/C-mediated proteolysis in budding yeast. Dieckhoff, P., Bolte, M., Sancak, Y., Braus, G.H., Irniger, S. Mol. Microbiol. (2004)
- Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents. Fasullo, M., Dong, Z., Sun, M., Zeng, L. DNA Repair (Amst.) (2005)
- Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Burton, J.L., Solomon, M.J. Genes Dev. (2007)
- Mec1p regulates Pds1p levels in S phase: complex coordination of DNA replication and mitosis. Clarke, D.J., Segal, M., Jensen, S., Reed, S.I. Nat. Cell Biol. (2001)
- Macromolecular assemblies regulate nonvesicular phosphatidylserine traffic in yeast. Choi, J.Y., Riekhof, W.R., Wu, W.I., Voelker, D.R. Biochem. Soc. Trans. (2006)
- The Saccharomyces cerevisiae PDS1 and RAD9 checkpoint genes control different DNA double-strand break repair pathways. DeMase, D., Zeng, L., Cera, C., Fasullo, M. DNA Repair (Amst.) (2005)
- Securin is not required for cellular viability, but is required for normal growth of mouse embryonic fibroblasts. Mei, J., Huang, X., Zhang, P. Curr. Biol. (2001)
- The Pds1 anaphase inhibitor and Mec1 kinase define distinct checkpoints coupling S phase with mitosis in budding yeast. Clarke, D.J., Segal, M., Mondésert, G., Reed, S.I. Curr. Biol. (1999)
- Destruction of the securin Pds1p occurs at the onset of anaphase during both meiotic divisions in yeast. Salah, S.M., Nasmyth, K. Chromosoma (2000)
- S-phase cyclins are required for a stable arrest at metaphase. Meyn, M.A., Holloway, S.L. Curr. Biol. (2000)
- IBD2 encodes a novel component of the Bub2p-dependent spindle checkpoint in the budding yeast Saccharomyces cerevisiae. Hwang, H.S., Song, K. Genetics (2002)
- The anaphase inhibitor Pds1 binds to the APC/C-associated protein Cdc20 in a destruction box-dependent manner. Hilioti, Z., Chung, Y.S., Mochizuki, Y., Hardy, C.F., Cohen-Fix, O. Curr. Biol. (2001)
- Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function. Wang, H., Liu, D., Wang, Y., Qin, J., Elledge, S.J. Genes Dev. (2001)
- A role for Saccharomyces cerevisiae Chk1p in the response to replication blocks. Schollaert, K.L., Poisson, J.M., Searle, J.S., Schwanekamp, J.A., Tomlinson, C.R., Sanchez, Y. Mol. Biol. Cell (2004)
- Abrogation of the Chk1-Pds1 checkpoint leads to tolerance of persistent single-strand breaks in Saccharomyces cerevisiae. Karumbati, A.S., Wilson, T.E. Genetics (2005)
- The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. Shirayama, M., Zachariae, W., Ciosk, R., Nasmyth, K. EMBO J. (1998)
- Dominant alleles of Saccharomyces cerevisiae CDC20 reveal its role in promoting anaphase. Schott, E.J., Hoyt, M.A. Genetics (1998)
- RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast. Gardner, R., Putnam, C.W., Weinert, T. EMBO J. (1999)
- Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae. Goh, P.Y., Surana, U. Mol. Cell. Biol. (1999)
- Dosage suppressors of pds1 implicate ubiquitin-associated domains in checkpoint control. Clarke, D.J., Mondesert, G., Segal, M., Bertolaet, B.L., Jensen, S., Wolff, M., Henze, M., Reed, S.I. Mol. Cell. Biol. (2001)
- Assaying the spindle checkpoint in the budding yeast Saccharomyces cerevisiae. Yellman, C.M., Burke, D.J. Methods Mol. Biol. (2004)