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Gene Review

INP52  -  phosphatidylinositol-3-/phosphoinositide 5...

Saccharomyces cerevisiae S288c

Synonyms: N2160, Polyphosphatidylinositol phosphatase INP52, SJL2, Synaptojanin-like protein 2, YNL106C
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High impact information on INP52


Biological context of INP52

  • The 5-phosphatase domains of synaptojanin, Inp52p, and Inp53p are also catalytic, thus representing the first examples of an inositol signaling protein with two distinct lipid phosphatase active sites within a single polypeptide chain [3].
  • Both inp51 inp52 and inp52 inp53 double mutants display compromised cell growth, whereas an inp51 inp53 double mutant does not [4].

Associations of INP52 with chemical compounds


Other interactions of INP52

  • Here we describe two related yeast loci, INP52 (YNL106c) and INP53 (YOR109w) [4].
  • Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae [4].


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