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Gene Review: 

EMILIN3  -  elastin microfibril interfacer 3

Homo sapiens

Synonyms: C20orf130, EMILIN-3, EMILIN-5, EMILIN5, Elastin microfibril interface-located protein 3, ...
 
 
 
 
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High impact information on EMILIN3

  • Western blotting detected EMILIN-5 expression in a variety of osteoblastic cell lines [1].
  • By analyzing expression profiles of human mesenchymal stem cells incubated in osteogenic supplements, we identified and characterized a novel human cDNA, elastin microfibril interface located protein-5 (EMILIN-5), that is likely to play a significant role in the process of osteogenesis [1].
  • The deduced EMILIN-5 product consists of 766 amino acids with a cysteine-rich EMI domain at the NH(2) terminus [1].
 

Analytical, diagnostic and therapeutic context of EMILIN3

  • Molecular cloning and characterization of a novel gene, EMILIN-5, and its possible involvement in skeletal development [1].
  • Immunohistochemistry of mouse embryos 13.5 days post-coitus revealed relatively high levels of EMILIN-5 protein in perichondrium cells of developing limbs [1].

References

  1. Molecular cloning and characterization of a novel gene, EMILIN-5, and its possible involvement in skeletal development. Doi, M., Nagano, A., Nakamura, Y. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
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