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Gene Review

GNS  -  class 1 transmembrane glycoprotein

Bovine ephemeral fever virus

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Disease relevance of GNS


High impact information on GNS

  • Less abundant mRNAs which appeared to initiate at consensus sequences immediately preceding and following the GNS ORF and terminate at the same polyadenylation signal were also detected [3].
  • The second ORF encodes a polypeptide of 609 residues with nine potential glycosylation sites which is most closely related to the BEFV non-structural glycoprotein (GNS) [3].

Analytical, diagnostic and therapeutic context of GNS

  • Multiple sequence alignments and phylogenetic analyses indicated that the ARV G and GNS glycoproteins, like those of BEFV, are structurally related and appear to have evolved at different rates from a common ancestral gene [3].


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