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MeSH Review:

Ephemeral Fever Virus, Bovine

Uren, M.F. et al., Cybinski, D.H. et al., McWilliam, S.M. et al., Farag, M.A. et al., Wallace, D.B. et al., et al.

Wallace, Viljoen,

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Disease relevance of Ephemeral Fever Virus, Bovine

Vaccinia virus-expressed bovine ephemeral fever virus G but not G(NS) glycoprotein induces neutralizing antibodies and protects against experimental infection [1].
Two separate recombinants were generated and selected for homogeneity expressing either the structural glycoprotein gene of bovine ephemeral fever virus (BEFV) or the two structural glycoprotein genes of Rift Valley fever virus (RVFV) [2].
Effective vaccination of cattle using the virion G protein of bovine ephemeral fever virus as an antigen [3].

High impact information on Ephemeral Fever Virus, Bovine

A 1622 nucleotide region of the bovine ephemeral fever virus (BEFV) genome, located between the second glycoprotein (GNS) gene and the polymerase (L) gene, has been cloned and sequenced in Australian (BB7721) and Chinese (Beijing-1) isolates of the virus [4].
Monoclonal antibodies (MAbs) were produced against the G, M2 and N proteins of bovine ephemeral fever virus (BEFV) and 29 were selected for further study [5].
In a series of experiments, the envelope glycoprotein (G protein) of bovine ephemeral fever virus (BEFV) induced immunity against challenge with virulent virus [3].
Serum neutralisation tests, which used a cell culture-adapted vaccine strain of bovine ephemeral fever virus as an antigen, revealed the presence of specific antibodies with significantly increased titres in the convalescent sera of affected animals [6].
Neutralizing antibody sensitive to 2-mercaptoethanol in cattle infected with bovine ephemeral fever virus [7].

Chemical compound and disease context of Ephemeral Fever Virus, Bovine

Mapping of antigenic sites on the bovine ephemeral fever virus glycoprotein using monoclonal antibodies [5].

References

Vaccinia virus-expressed bovine ephemeral fever virus G but not G(NS) glycoprotein induces neutralizing antibodies and protects against experimental infection. Hertig, C., Pye, A.D., Hyatt, A.D., Davis, S.S., McWilliam, S.M., Heine, H.G., Walker, P.J., Boyle, D.B. J. Gen. Virol. (1996) [Pubmed]
Immune responses to recombinants of the South African vaccine strain of lumpy skin disease virus generated by using thymidine kinase gene insertion. Wallace, D.B., Viljoen, G.J. Vaccine (2005) [Pubmed]
Effective vaccination of cattle using the virion G protein of bovine ephemeral fever virus as an antigen. Uren, M.F., Walker, P.J., Zakrzewski, H., St George, T.D., Byrne, K.A. Vaccine (1994) [Pubmed]
Genome organization and transcription strategy in the complex GNS-L intergenic region of bovine ephemeral fever rhabdovirus. McWilliam, S.M., Kongsuwan, K., Cowley, J.A., Byrne, K.A., Walker, P.J. J. Gen. Virol. (1997) [Pubmed]
Mapping of antigenic sites on the bovine ephemeral fever virus glycoprotein using monoclonal antibodies. Cybinski, D.H., Walker, P.J., Byrne, K.A., Zakrzewski, H. J. Gen. Virol. (1990) [Pubmed]
Epizootics of bovine ephemeral fever on dairy farms in Saudi Arabia. Farag, M.A., al-Sukayran, A., Mazloum, K.S., al-Bukomy, A.M. Rev. - Off. Int. Epizoot. (1998) [Pubmed]
Neutralizing antibody sensitive to 2-mercaptoethanol in cattle infected with bovine ephemeral fever virus. Kurogi, H., Inaba, Y., Takahashi, E., Sato, K., Fusato, S., Taniguchi, S., Satoda, K., Omori, T. National Institute of Animal Health quarterly. (1977) [Pubmed]

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