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UBE2Q2  -  ubiquitin-conjugating enzyme E2Q family...

Homo sapiens

Synonyms: DKFZp762C143, Ubiquitin carrier protein Q2, Ubiquitin-conjugating enzyme E2 Q2, Ubiquitin-protein ligase Q2
 
 
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High impact information on UBE2Q2

  • This implantation site-specific expression of UBE2Q2 in luminal epithelial cells could play major roles in orchestrating differentiation events through the modification of specific protein substrates [1].
  • We recently identified a differentially expressed gene in implantation stage rabbit endometrium encoding a new member of the ubiquitin-conjugating enzyme family designated UBE2Q2 (also known as UBCi) [1].
 

Anatomical context of UBE2Q2

  • Affinity-purified antibodies prepared with purified recombinant UBE2Q2 showed that the protein was undetectable by immunoblot analysis in endometrial lysates from estrous and Day 6(3/4) pregnant (blastocyst attachment stage) rabbits but was expressed in both mesometrial and antimesometrial implantation site endometrium of Day 8 pregnant animals [1].
 

Analytical, diagnostic and therapeutic context of UBE2Q2

References

  1. Demonstration of ubiquitin thiolester formation of UBE2Q2 (UBCi), a novel ubiquitin-conjugating enzyme with implantation site-specific expression. Melner, M.H., Haas, A.L., Klein, J.M., Brash, A.R., Boeglin, W.E., Nagdas, S.K., Winfrey, V.P., Olson, G.E. Biol. Reprod. (2006) [Pubmed]
 
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