Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

hrcA - heat-inducible transcription repressor

Streptococcus pneumoniae R6

Oggioni, M.R. et al., Kim, S.N. et al.

Oggioni, Trappetti, Kadioglu, Cassone, Iannelli, Ricci, Andrew, Pozzi,

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High impact information on hrcA

Gene expression in blood was characterized by increased expression of pneumolysin, pspA and hrcA, while pneumococci in tissue infection showed increased expression of neuraminidases, metalloproteinases, oxidative stress and competence genes [1].
The putative negative regulator of the groEL gene, hrcA, of S. pneumoniae was recovered by PCR-based chromosomal walking from grpE locus [2].

References

Switch from planktonic to sessile life: a major event in pneumococcal pathogenesis. Oggioni, M.R., Trappetti, C., Kadioglu, A., Cassone, M., Iannelli, F., Ricci, S., Andrew, P.W., Pozzi, G. Mol. Microbiol. (2006) [Pubmed]
Molecular cloning and characterization of groESL operon in Streptococcus pneumoniae. Kim, S.N., Kim, S.W., Pyo, S.N., Rhee, D.K. Mol. Cells (2001) [Pubmed]

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