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Gene Review:

CP - coat protein

Physalis mottle virus

Jacob, A.N. et al., Yoshii, M. et al., Umashankar, M. et al., Martelli, G.P. et al.

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Disease relevance of CP

Accumulation of CMV CP in the inoculated leaves of cum1-1 plants was also delayed either when CMV virion or CMV virion RNA was inoculated [1].
Replication-associated proteins and CP are phylogenetically related to those of members of the genera Tymovirus and Marafivirus [2].

High impact information on CP

Genetic analyses suggested that the phenotype of delayed accumulation of CMV CP in the mutant plants was caused by a single, nuclear and recessive mutation designated cum1-1, which was located on chromosome IV [1].
Physalis mottle tymovirus (PhMV) is a small spherical plant virus with its RNA genome encapsidated in a protein shell made of 180 identical coat protein (CP) subunits [3].
In addition, the sequence upstream of the CP gene contains the message coding for 178 amino acid residues of the C-terminus of the putative replicase protein (RP) [4].
The open reading frame (ORF) at the 3' terminus corresponds to the amino acid sequence of the coat protein (CP) determined earlier except for the absence of the dipeptide, Lys-Leu, at position 110-111 [4].

References

Isolation of an Arabidopsis thaliana mutant in which accumulation of cucumber mosaic virus coat protein is delayed. Yoshii, M., Yoshioka, N., Ishikawa, M., Naito, S. Plant J. (1998) [Pubmed]
Maculavirus, a new genus of plant viruses. Martelli, G.P., Sabanadzovic, S., Abou Ghanem-Sabanadzovic, N., Saldarelli, P. Arch. Virol. (2002) [Pubmed]
The role of inter-subunit ionic interactions in the assembly of Physalis mottle tymovirus. Umashankar, M., Murthy, M.R., Singh, S.A., Appu Rao, A.G., Savithri, H.S. Arch. Virol. (2006) [Pubmed]
Nucleotide sequence of the 3' terminal region of belladonna mottle virus-Iowa (renamed Physalis mottle virus) RNA and an analysis of the relationships of tymoviral coat proteins. Jacob, A.N., Murthy, M.R., Savithri, H.S. Arch. Virol. (1992) [Pubmed]

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