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Gene Review:

kgtP - alpha-ketoglutarate transporter

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2585, JW2571, witA

Seol, W. et al., Culham, D.E. et al.

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Disease relevance of kgtP

Escherichia coli kgtP encodes an alpha-ketoglutarate transporter [1].

High impact information on kgtP

Growth on alpha-ketoglutarate and uptake of alpha-[14C]ketoglutarate were restored by transformation with plasmids containing witA [1].
The witA gene located between pss and rrnG on the Escherichia coli chromosome encodes a 432-amino acid protein [1].
Multiple alignment revealed particularly close correspondence among the ProP protein, citrate transporters from E. coli and Klebsiella pneumoniae and an alpha-ketoglutarate transporter from E. coli [2].

References

Escherichia coli kgtP encodes an alpha-ketoglutarate transporter. Seol, W., Shatkin, A.J. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
Isolation and sequencing of Escherichia coli gene proP reveals unusual structural features of the osmoregulatory proline/betaine transporter, ProP. Culham, D.E., Lasby, B., Marangoni, A.G., Milner, J.L., Steer, B.A., van Nues, R.W., Wood, J.M. J. Mol. Biol. (1993) [Pubmed]

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