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Gene Review

flgJ  -  flagellar rod assembly protein and murein...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1066, JW1068, flaZ
 
 
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Disease relevance of flgJ

  • Isolation of fla-lacZ fusions in Escherichia coli K-12: most fusions result in soluble beta-galactosidase [1].
  • The analytical sensitivity of the assay is comparable to that of previously described nested PCR assays (A. phagocytophilum, 16S rRNA; B. burgdorferi, fla gene), amplifying the equivalent of one-eighth of an A. phagocytophilum-infected cell and 50 borrelia spirochetes [2].
 

High impact information on flgJ

  • Analysis of a chimeric flgJ-NPT II transcriptional fusion showed that the flgJ regulatory sequences do not control the segregation of the 29K flagellin to the swarmer cell progeny, suggesting that correct segregation depends on the protein product [3].

References

  1. Isolation of fla-lacZ fusions in Escherichia coli K-12: most fusions result in soluble beta-galactosidase. Komeda, Y. J. Bacteriol. (1988) [Pubmed]
  2. Multiplex real-time PCR for detection of anaplasma phagocytophilum and Borrelia burgdorferi. Courtney, J.W., Kostelnik, L.M., Zeidner, N.S., Massung, R.F. J. Clin. Microbiol. (2004) [Pubmed]
  3. Control of synthesis and positioning of a Caulobacter crescentus flagellar protein. Loewy, Z.G., Bryan, R.A., Reuter, S.H., Shapiro, L. Genes Dev. (1987) [Pubmed]
 
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