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Gene Review

rhaR  -  transcriptional activator of rhaSR

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3899, JW3877, rhaC1
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Disease relevance of rhaR

  • The precise location of the rhaT gene, encoding rhamnose permease, has been established between sodA and rhaC at 3605-3607 kb of Kohara's physical map, which corresponds to 88.4 min on the Escherichia coli chromosomal map [1].

High impact information on rhaR

  • The product of the rhaR gene, which regulates the level of mRNA produced from the four L-rhamnose-inducible promoters of the rhamnose operon, has been hypersynthesized and purified by a two-column procedure [2].
  • The rhaC gene, whose product is the positive activator of the genes required for L-rhamnose utilization, has been cloned along with the rhamnose structural genes [3].
  • The rhaC sequence shows two partially overlapping reading frames, encoding two proteins of molecular weight 32,000 and 35,000 RhaS and RhaR [3].


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