Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

rhaT - L-rhamnose:proton symporter

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3900, JW3878

Baldomá, L. et al., Garcia-Martin, C. et al., Vía, P. et al., Tate, C.G. et al.

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Disease relevance of rhaT

Cloning, mapping and gene product identification of rhaT from Escherichia coli K12 [1].
This strain was used to isolate a clone of Salmonella typhimurium DNA that encoded L-rhamnose-H+ transport activity, the gene for which, rhaT, was sequenced [2].

High impact information on rhaT

Transcriptional regulation of the rhaT gene, one of the operons forming the rhamnose regulon in Escherichia coli, was studied by fusing its complete or deleted promoter to the reporter gene lacZ [3].
The structural gene, rhaT, encoding the rhamnose permease has been cloned from Escherichia coli. rhaT has been mapped in the rha locus (87.7 min) by analysis of cotransduction with glpK and other rha markers [1].
Nucleotide sequence of the rhaR-sodA interval specifying rhaT in Escherichia coli [4].

Biological context of rhaT

The sequence of the sodA-rhaC interval displayed a single ORF corresponding to rhaT, which is transcribed counterclockwise on the E. coli chromosome [4].

References

Cloning, mapping and gene product identification of rhaT from Escherichia coli K12. Baldomá, L., Badía, J., Sweet, G., Aguilar, J. FEMS Microbiol. Lett. (1990) [Pubmed]
Mapping, cloning, expression, and sequencing of the rhaT gene, which encodes a novel L-rhamnose-H+ transport protein in Salmonella typhimurium and Escherichia coli. Tate, C.G., Muiry, J.A., Henderson, P.J. J. Biol. Chem. (1992) [Pubmed]
Transcriptional regulation of the Escherichia coli rhaT gene. Vía, P., Badía, J., Baldomà, L., Obradors, N., Aguilar, J. Microbiology (Reading, Engl.) (1996) [Pubmed]
Nucleotide sequence of the rhaR-sodA interval specifying rhaT in Escherichia coli. Garcia-Martin, C., Baldomà, L., Badía, J., Aguilar, J. J. Gen. Microbiol. (1992) [Pubmed]

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