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Gene Review

dnaK  -  molecular chaperone DnaK

Synechocystis sp. PCC 6803

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Disease relevance of dnaK

 

High impact information on dnaK

  • There was a close correlation between thylakoid fluidity levels, monitored by steady-state 1,6-diphenyl-1,3,5-hexatriene anisotropy, and threshold temperatures required for maximal activation of all of the HS-inducible genes investigated, including dnaK, groESL, cpn60, and hsp17 [2].

References

  1. Improvement of the bioluminescence reporter system for real-time monitoring of circadian rhythms in the cyanobacterium Synechocystis sp. strain PCC 6803. Kucho, K., Aoki, K., Itoh, S., Ishiura, M. Genes Genet. Syst. (2005) [Pubmed]
  2. Membrane physical state controls the signaling mechanism of the heat shock response in Synechocystis PCC 6803: identification of hsp17 as a "fluidity gene". Horváth, I., Glatz, A., Varvasovszki, V., Török, Z., Páli, T., Balogh, G., Kovács, E., Nádasdi, L., Benkö, S., Joó, F., Vígh, L. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
 
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