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Gene Review

uvrA  -  excinuclease ABC subunit A

Escherichia coli O157:H7 str. EDL933

 
 
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Disease relevance of uvrA

  • Identification and characterization of two uvrA genes of Xanthomonas axonopodis pathovar citri [1].
  • In spite of this inability to repair UV damaged DNA, uvrA, uvrB and uvrC deletion mutants are substantially less UV sensitive than excision repair mutants of E. coli or yeast [2].
 

High impact information on uvrA

References

  1. Identification and characterization of two uvrA genes of Xanthomonas axonopodis pathovar citri. Shen, C.H., Chiang, Y.C., Hsu, C.H., Yang, M.K. Mol. Genet. Genomics (2007) [Pubmed]
  2. The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1. Crowley, D.J., Boubriak, I., Berquist, B.R., Clark, M., Richard, E., Sullivan, L., Dassarma, S., McCready, S. Saline Syst. (2006) [Pubmed]
  3. Role of DNA replication and repair in thymineless death in Escherichia coli. Morganroth, P.A., Hanawalt, P.C. J. Bacteriol. (2006) [Pubmed]
 
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