The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Encephalitis Virus, Eastern Equine

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Encephalitis Virus, Eastern Equine

  • Comparative analysis of structural virion polypeptides of 24 selected EEE virus strains, representing North and South American types, was performed by one-dimensional discontinuous sodium dodecyl sulfate (SDS)-polyacrylamide-gel electrophoresis (PAGE) [1].
  • The structural proteins of different EEE virus isolates, resolved by this method, exhibited mol.wts. values in the range of 57-60 X 10(3) for (E-1), 51-54 X 10(3) for (E-2) and 35-38 X 10(3) daltons for the core (NP) nucleocapsid [1].

High impact information on Encephalitis Virus, Eastern Equine

  • Both the HMW protein and the E2 protein (doublet) of EEE virus appeared to contain, at least in part, high-mannose type N-linked oligosaccharides [2].
  • Transmembrane domains present in the EEE virus structural polyprotein have been identified and their functions discussed [3].
  • In view of these findings, we have examined the reactivity of sera from three individuals immunized with the EEE vaccine, derived from an NA isolate, with field strains of EEE virus [4].
  • This test also detected EEE virus in formalin-fixed avian brain [5].
  • Cross-reactive epitopes were localised within five different sites of glycoprotein E2 of VEE virus and within four sites of that of the EEE virus [6].

Chemical compound and disease context of Encephalitis Virus, Eastern Equine


Gene context of Encephalitis Virus, Eastern Equine

  • A highly conserved domain (C domain) forming alphavirus-group-reactive MAbs was identified in the E2 protein of the VEE and EEE viruses [8].


  1. Virion polypeptide heterogeneity among virulent and avirulent strains of eastern equine encephalitis (EEE) virus. Walder, R., Rosato, R.R., Eddy, G.A. Arch. Virol. (1981) [Pubmed]
  2. Structural protein relationships among eastern equine encephalitis viruses. Strizki, J.M., Repik, P.M. J. Gen. Virol. (1994) [Pubmed]
  3. Nucleotide sequence of the genome region encoding the 26S mRNA of eastern equine encephalomyelitis virus and the deduced amino acid sequence of the viral structural proteins. Chang, G.J., Trent, D.W. J. Gen. Virol. (1987) [Pubmed]
  4. Differential reactivity of immune sera from human vaccinees with field strains of eastern equine encephalitis virus. Strizki, J.M., Repik, P.M. Am. J. Trop. Med. Hyg. (1995) [Pubmed]
  5. Diagnosis of eastern equine encephalitis by immunohistochemistry in two flocks of Michigan ring-neck pheasants. Williams, S.M., Fulton, R.M., Patterson, J.S., Reed, W.M. Avian Dis. (2000) [Pubmed]
  6. Glycoproteins E2 of the Venezuelan and eastern equine encephalomyelitis viruses contain multiple cross-reactive epitopes. Pereboev, A.V., Razumov, I.A., Svyatchenko, V.A., Loktev, V.B. Arch. Virol. (1996) [Pubmed]
  7. Detection of eastern equine encephalomyelitis virus RNA in formalin-fixed, paraffin-embedded tissues using DNA in situ hybridization. Gregory, C.R., Latimer, K.S., Niagro, F.D., Campagnoli, R.P., Steffens, W.L., Ritchie, B.W. J. Vet. Diagn. Invest. (1996) [Pubmed]
  8. Analysis of the hemagglutination activity domains of the Venezuelan equine encephalomyelitis and eastern equine encephalomyelitis viruses. Razumov, I.A., Khusainova, A.D., Agapov, E.V., Gaidamovich SYa, n.u.l.l., Pereboev, A.V., Kolykhalov, A.A., Netesov, S.V., Loktev, V.B. Intervirology (1994) [Pubmed]
WikiGenes - Universities