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MeSH Review:

Naturopathy

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High impact information on Naturopathy

Celastrol, an active compound extracted from the root bark of the Chinese medicine "Thunder of God Vine" (Tripterygium wilfordii Hook F.), was used for years as a natural remedy for inflammatory conditions [1].
S-adenosyl-L-methionine (SAMe) is one of the better studied of the natural remedies [2].
The disease has been treatable by a natural remedy, quinine, since the 17th century, but the production of synthetic antimalarial agents was first achieved in Germany in the wake of the Great War of 1914-1918, in which malaria had caused immense problems [3].
Phytosterols or plant sterols (PS) are consumed as natural remedies and margarines by the general population in developed countries to lower elevated serum cholesterol levels [4].
Phytosterols (PS) are the analogues of animal cholesterol in various plants. beta-Sitosterol is a PS used in margarines and natural remedies to lower elevated serum cholesterol levels [5].

Associations of Naturopathy with chemical compounds

Expected treatment was: cough suppressants (64%), anti-congestants (57%), paracetamol (56%), natural remedies (53%) and antibiotics (25%) [6].

Gene context of Naturopathy

Herbals and other natural remedies could affect the disposition of conventional pharmaceuticals through inhibition of human cytochrome P-450 (CYP) enzymes [7].
Is there a role for natural remedies in rheumatoid arthritis [8]?

References

Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. Yang, H., Chen, D., Cui, Q.C., Yuan, X., Dou, Q.P. Cancer Res. (2006) [Pubmed]
Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Mischoulon, D., Fava, M. Am. J. Clin. Nutr. (2002) [Pubmed]
Conflicts of interest: the genesis of synthetic antimalarial agents in peace and war. Greenwood, D. J. Antimicrob. Chemother. (1995) [Pubmed]
Phytosterols act as endocrine and metabolic disruptors in the European polecat (Mustela putorius). Nieminen, P., Mustonen, A.M., Lindström-Seppä, P., Asikainen, J., Mussalo-Rauhamaa, H., Kukkonen, J.V. Toxicol. Appl. Pharmacol. (2002) [Pubmed]
Effects of phytosterols on the endocrinology and metabolism of the female raccoon dog (Nyctereutes procyonoides). Nieminen, P., Mustonen, A.M., Asikainen, J., Kukkonen, J.V., Lindström-Seppä, P., Kärkkäinen, V. J. Toxicol. Environ. Health Part A (2003) [Pubmed]
The knowledge and expectations of parents about the role of antibiotic treatment in upper respiratory tract infection--a survey among parents attending the primary physician with their sick child. Shlomo, V., Adi, R., Eliezer, K. BMC family practice [electronic resource]. (2003) [Pubmed]
An approach to the in vitro evaluation of potential for cytochrome P450 enzyme inhibition from herbals and other natural remedies. Strandell, J., Neil, A., Carlin, G. Phytomedicine (2004) [Pubmed]
Is there a role for natural remedies in rheumatoid arthritis? Belch, J.J. Scottish medical journal. (1992) [Pubmed]

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