Disease relevance of Hyperbilirubinemia, Hereditary

• Erythrocyte membrane transport of glutathione conjugates and oxidized glutathione in the Dubin-Johnson syndrome and in rats with hereditary hyperbilirubinemia [1].
• Coinheritance of Rotor syndrome, G-6-PD deficiency, and heterozygous beta thalassemia: a possible genetic interaction [2].

High impact information on Hyperbilirubinemia, Hereditary

• Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia [3].
• The nicotinic acid test was also performed before and after corticosteroid treatment in four patients with Dubin-Johnson or Rotor syndrome [4].
• Bilirubin metabolism and the hereditary hyperbilirubinemias [5].
• Bile acid clearance in sheep with hereditary hyperbilirubinemia [6].
• In contrast, biliary excretion of BSP and its conjugates was not impaired and regurgitation of conjugated BSP into plasma was minimal in the Rotor syndrome [7].

Chemical compound and disease context of Hyperbilirubinemia, Hereditary

• A 2-year-old boy with Rotor syndrome was studied with Tc-99m N-(di-isopropylphenyl carbamoylmethyl) iminodiacetic acid (DIPA) [8].

Gene context of Hyperbilirubinemia, Hereditary

• It is concluded that Tc-99m DIPA cholescintigraphy may be helpful in the diagnosis of Rotor syndrome [8].

References