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MeSH Review:

Phosphenes

Delbeke, J. et al., Khedr, E.M. et al., Brighina, F. et al., Loewenstein, J.I. et al., Ray, P.G. et al.

Loewenstein, Montezuma, Rizzo, Khedr, Ahmed, Mohamed,

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Psychiatry related information on Phosphenes

The resulting strength-duration relationship for somatosensory, phosphene, and pain threshold has been recorded in five RP patients as well as in 10 healthy volunteers [1].

High impact information on Phosphenes

In RP patients, however, phosphenes are not so easily obtained [1].
Stimulation of sites lateral to the midline elicited phosphenes in the contralateral visual field [2].
Each subject underwent transcranial magnetic stimulation and was submitted to the following: determination of resting motor threshold (rMT), silent period (SP), MEP input-output curves, phosphene threshold (PT) [3].
In all but one patient unable to perceive phosphenes (42% vs. 50% of controls), TMS at 100% intensity did not elicit motor response at rest [4].

Analytical, diagnostic and therapeutic context of Phosphenes

Electrical stimulation can produce phosphenes in the eyes of individuals who are blind as a result of retinitis pigmentosa [5].

References

Electrical stimulation of anterior visual pathways in retinitis pigmentosa. Delbeke, J., Pins, D., Michaux, G., Wanet-Defalque, M.C., Parrini, S., Veraart, C. Invest. Ophthalmol. Vis. Sci. (2001) [Pubmed]
Magnetic stimulation of visual cortex: factors influencing the perception of phosphenes. Ray, P.G., Meador, K.J., Epstein, C.M., Loring, D.W., Day, L.J. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. (1998) [Pubmed]
Motor and visual cortical excitability in migraineurs patients with or without aura: transcranial magnetic stimulation. Khedr, E.M., Ahmed, M.A., Mohamed, K.A. Neurophysiologie clinique = Clinical neurophysiology. (2006) [Pubmed]
Hypo-excitability of cortical areas in patients affected by Friedreich ataxia: a TMS study. Brighina, F., Scalia, S., Gennuso, M., Lupo, I., Matta, F., Piccoli, T., Fierro, B. J. Neurol. Sci. (2005) [Pubmed]
Outer retinal degeneration: an electronic retinal prosthesis as a treatment strategy. Loewenstein, J.I., Montezuma, S.R., Rizzo, J.F. Arch. Ophthalmol. (2004) [Pubmed]

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