Gene Review:
MID1 - midline 1
Homo sapiens
Synonyms:
BBBG1, E3 ubiquitin-protein ligase Midline-1, FXY, GBBB1, MIDIN, ...
Aftanas,
Golocheikine,
Schweiger,
Foerster,
Lehmann,
Suckow,
Muller,
Walter,
Davies,
Porter,
van Bokhoven,
Lunt,
Traub,
Ropers,
Condron,
Lemke,
Cox,
Allen,
Cox,
Hopwood,
Goodwin,
Haan,
Suthers,
Short,
Hopwood,
Yi,
Cox,
Colmenares,
Heilstedt,
Shaffer,
Schwartz,
Berk,
Murray,
Stavnezer,
Brody,
Mandelkern,
London,
Childress,
Lee,
Bota,
Ho,
Saxena,
Baxter,
Madsen,
Jarvik,
Jeffery,
Kalscheuer,
Freude,
Musante,
Jensen,
Yntema,
Gécz,
Sefiani,
Hoffmann,
Moser,
Haas,
Gurok,
Haesler,
Aranda,
Nshedjan,
Tzschach,
Hartmann,
Roloff,
Shoichet,
Hagens,
Tao,
Van Bokhoven,
Turner,
Chelly,
Moraine,
Fryns,
Nuber,
Hoeltzenbein,
Scharff,
Scherthan,
Lenzner,
Hamel,
Schweiger,
Ropers,
Graham,
Wheeler,
Tackels-Horne,
Lin,
Hall,
May,
Short,
Schwartz,
Cox,
Odent,
Atti-Bitach,
Blayau,
Mathieu,
Aug,
Delezo de,
Gall,
Le Marec,
Munnich,
David,
Vekemans,
- Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22. Quaderi, N.A., Schweiger, S., Gaudenz, K., Franco, B., Rugarli, E.I., Berger, W., Feldman, G.J., Volta, M., Andolfi, G., Gilgenkrantz, S., Marion, R.W., Hennekam, R.C., Opitz, J.M., Muenke, M., Ropers, H.H., Ballabio, A. Nat. Genet. (1997)
- FXY2/MID2, a gene related to the X-linked Opitz syndrome gene FXY/MID1, maps to Xq22 and encodes a FNIII domain-containing protein that associates with microtubules. Perry, J., Short, K.M., Romer, J.T., Swift, S., Cox, T.C., Ashworth, A. Genomics (1999)
- X-linked Opitz syndrome: novel mutations in the MID1 gene and redefinition of the clinical spectrum. De Falco, F., Cainarca, S., Andolfi, G., Ferrentino, R., Berti, C., Rodríguez Criado, G., Rittinger, O., Dennis, N., Odent, S., Rastogi, A., Liebelt, J., Chitayat, D., Winter, R., Jawanda, H., Ballabio, A., Franco, B., Meroni, G. Am. J. Med. Genet. A (2003)
- The Opitz syndrome gene product, MID1, associates with microtubules. Schweiger, S., Foerster, J., Lehmann, T., Suckow, V., Muller, Y.A., Walter, G., Davies, T., Porter, H., van Bokhoven, H., Lunt, P.W., Traub, P., Ropers, H.H. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4. Liu, J., Prickett, T.D., Elliott, E., Meroni, G., Brautigan, D.L. Proc. Natl. Acad. Sci. U.S.A. (2001)
- The role of the floor plate in axon guidance. Colamarino, S.A., Tessier-Lavigne, M. Annu. Rev. Neurosci. (1995)
- Species-typical behavior of hamsters deprived from birth of the neocortex. Murphy, M.R., MacLean, P.D., Hamilton, S.C. Science (1981)
- Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome. Niemitz, E.L., DeBaun, M.R., Fallon, J., Murakami, K., Kugoh, H., Oshimura, M., Feinberg, A.P. Am. J. Hum. Genet. (2004)
- Equivalent forgetting rates in long-term memory for diencephalic and medial temporal lobe amnesia. McKee, R.D., Squire, L.R. J. Neurosci. (1992)
- Volition to action--an event-related fMRI study. Winterer, G., Adams, C.M., Jones, D.W., Knutson, B. Neuroimage (2002)
- Architecture of the optic chiasm and the mechanisms that sculpt its development. Jeffery, G. Physiol. Rev. (2001)
- SOX3 is required during the formation of the hypothalamo-pituitary axis. Rizzoti, K., Brunelli, S., Carmignac, D., Thomas, P.Q., Robinson, I.C., Lovell-Badge, R. Nat. Genet. (2004)
- Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation. Kalscheuer, V.M., Freude, K., Musante, L., Jensen, L.R., Yntema, H.G., Gécz, J., Sefiani, A., Hoffmann, K., Moser, B., Haas, S., Gurok, U., Haesler, S., Aranda, B., Nshedjan, A., Tzschach, A., Hartmann, N., Roloff, T.C., Shoichet, S., Hagens, O., Tao, J., Van Bokhoven, H., Turner, G., Chelly, J., Moraine, C., Fryns, J.P., Nuber, U., Hoeltzenbein, M., Scharff, C., Scherthan, H., Lenzner, S., Hamel, B.C., Schweiger, S., Ropers, H.H. Nat. Genet. (2003)
- Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski-/- mice. Colmenares, C., Heilstedt, H.A., Shaffer, L.G., Schwartz, S., Berk, M., Murray, J.C., Stavnezer, E. Nat. Genet. (2002)
- Delayed pentobarbital administration limits ischemic brain damage in gerbils. Levy, D.E., Brierley, J.B. Ann. Neurol. (1979)
- Parallel processing of proprioceptive signals by spiking local interneurons and motor neurons in the locust. Burrows, M. J. Neurosci. (1987)
- Antineutrophil cytoplasmic antibodies reacting with human neutrophil elastase as a diagnostic marker for cocaine-induced midline destructive lesions but not autoimmune vasculitis. Wiesner, O., Russell, K.A., Lee, A.S., Jenne, D.E., Trimarchi, M., Gregorini, G., Specks, U. Arthritis Rheum. (2004)
- Adenocarcinoma developing in a patient with midline granuloma. Meyer, T.J., Stanford, R.E., Pearlman, N. Arch. Intern. Med. (1983)
- Steroid-induced CT changes in patients with recurrent malignant glioma. Cairncross, J.G., Macdonald, D.R., Pexman, J.H., Ives, F.J. Neurology (1988)
- MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation. Trockenbacher, A., Suckow, V., Foerster, J., Winter, J., Krauss, S., Ropers, H.H., Schneider, R., Schweiger, S. Nat. Genet. (2001)
- Opitz G/BBB syndrome in Xp22: mutations in the MID1 gene cluster in the carboxy-terminal domain. Gaudenz, K., Roessler, E., Quaderi, N., Franco, B., Feldman, G., Gasser, D.L., Wittwer, B., Horst, J., Montini, E., Opitz, J.M., Ballabio, A., Muenke, M. Am. J. Hum. Genet. (1998)
- New mutations in MID1 provide support for loss of function as the cause of X-linked Opitz syndrome. Cox, T.C., Allen, L.R., Cox, L.L., Hopwood, B., Goodwin, B., Haan, E., Suthers, G.K. Hum. Mol. Genet. (2000)
- The Opitz syndrome gene MID1 is essential for establishing asymmetric gene expression in Hensen's node. Granata, A., Quaderi, N.A. Dev. Biol. (2003)
- MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders. Short, K.M., Hopwood, B., Yi, Z., Cox, T.C. BMC Cell Biol. (2002)
- Cooperation of BMP7 and SHH in the induction of forebrain ventral midline cells by prechordal mesoderm. Dale, J.K., Vesque, C., Lints, T.J., Sampath, T.K., Furley, A., Dodd, J., Placzek, M. Cell (1997)
- Control of retinal ganglion cell axon growth: a new role for Sonic hedgehog. Trousse, F., Martí, E., Gruss, P., Torres, M., Bovolenta, P. Development (2001)
- A comparison of injections of botulinum toxin and topical nitroglycerin ointment for the treatment of chronic anal fissure. Brisinda, G., Maria, G., Bentivoglio, A.R., Cassetta, E., Gui, D., Albanese, A. N. Engl. J. Med. (1999)
- Glial control of neuronal development. Lemke, G. Annu. Rev. Neurosci. (2001)
- Serotonergic neurons transiently require a midline-derived FGF signal. Condron, B.G. Neuron (1999)
- Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin. Engelking, L.J., Evers, B.M., Richardson, J.A., Goldstein, J.L., Brown, M.S., Liang, G. J. Clin. Invest. (2006)
- Brain metabolic changes during cigarette craving. Brody, A.L., Mandelkern, M.A., London, E.D., Childress, A.R., Lee, G.S., Bota, R.G., Ho, M.L., Saxena, S., Baxter, L.R., Madsen, D., Jarvik, M.E. Arch. Gen. Psychiatry (2002)
- Netrin/DCC signaling controls contralateral dendrites of octavolateralis efferent neurons. Suli, A., Mortimer, N., Shepherd, I., Chien, C.B. J. Neurosci. (2006)
- Coordinate expression of Fgf8, Otx2, Bmp4, and Shh in the rostral prosencephalon during development of the telencephalic and optic vesicles. Crossley, P.H., Martinez, S., Ohkubo, Y., Rubenstein, J.L. Neuroscience (2001)
- The migration of cerebellar rhombic lip derivatives. Gilthorpe, J.D., Papantoniou, E.K., Chédotal, A., Lumsden, A., Wingate, R.J. Development (2002)
- Drosophila center divider gene is expressed in CNS midline cells and encodes a developmentally regulated protein kinase orthologous to human TESK1. Matthews, B.B., Crews, S.T. DNA Cell Biol. (1999)
- Human anterior and frontal midline theta and lower alpha reflect emotionally positive state and internalized attention: high-resolution EEG investigation of meditation. Aftanas, L.I., Golocheikine, S.A. Neurosci. Lett. (2001)
- MID2, a homologue of the Opitz syndrome gene MID1: similarities in subcellular localization and differences in expression during development. Buchner, G., Montini, E., Andolfi, G., Quaderi, N., Cainarca, S., Messali, S., Bassi, M.T., Ballabio, A., Meroni, G., Franco, B. Hum. Mol. Genet. (1999)
- A new X-linked syndrome with agenesis of the corpus callosum, mental retardation, coloboma, micrognathia, and a mutation in the Alpha 4 gene at Xq13. Graham, J.M., Wheeler, P., Tackels-Horne, D., Lin, A.E., Hall, B.D., May, M., Short, K.M., Schwartz, C.E., Cox, T.C. Am. J. Med. Genet. A (2003)
- The Opitz syndrome gene Mid1 is transcribed from a human endogenous retroviral promoter. Landry, J.R., Rouhi, A., Medstrand, P., Mager, D.L. Mol. Biol. Evol. (2002)
- Expression of the Sonic hedgehog (SHH ) gene during early human development and phenotypic expression of new mutations causing holoprosencephaly. Odent, S., Atti-Bitach, T., Blayau, M., Mathieu, M., Aug, J., Delezo de, A.L., Gall, J.Y., Le Marec, B., Munnich, A., David, V., Vekemans, M. Hum. Mol. Genet. (1999)
- Functional characterization of the Opitz syndrome gene product (midin): evidence for homodimerization and association with microtubules throughout the cell cycle. Cainarca, S., Messali, S., Ballabio, A., Meroni, G. Hum. Mol. Genet. (1999)
- BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Moser, M., Binder, O., Wu, Y., Aitsebaomo, J., Ren, R., Bode, C., Bautch, V.L., Conlon, F.L., Patterson, C. Mol. Cell. Biol. (2003)
- Genetic analysis as an aid in diagnosis for patients with midline carcinomas of uncertain histologies. Motzer, R.J., Rodriguez, E., Reuter, V.E., Samaniego, F., Dmitrovsky, E., Bajorin, D.F., Pfister, D.G., Parsa, N.Z., Chaganti, R.S., Bosl, G.J. J. Natl. Cancer Inst. (1991)
- Influence of abdominal-wound closure technique on complications after surgery: a randomised study. Niggebrugge, A.H., Trimbos, J.B., Hermans, J., Steup, W.H., Van De Velde, C.J. Lancet (1999)