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MeSH Review

Medication Errors

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Disease relevance of Medication Errors


High impact information on Medication Errors

  • Unlike previously recommended dose regimens for lidocaine, this technique uses an exponentially declining infusion and has the advantages of greater simplicity, less chance of medication error, and avoidance of rapid changes of lidocaine concentrations [2].
  • Of the 7 studies evaluating isolated CDSSs, 3 demonstrated statistically significant improvements in antibiotic-associated medication errors or adverse drug events and 1 an improvement in theophylline-associated medication errors [3].
  • Very few studies have investigated the incidence of medication errors associated with parenteral drug administration [4].
  • Medication errors were associated with the use of five or more medications, and the unusual schedule of administration of low dose MTX may also have been contributory [5].
  • RESULTS: Gout medication errors occurred in 39% (n = 273) of facilities participating in the MEDMARX program [6].

Associations of Medication Errors with chemical compounds


Gene context of Medication Errors

  • Most importantly, 30-day mortality was significantly higher in patients with medication errors: For t-PA dosing errors, mortality was 7.7% versus 5.5% for patients who received the correct t-PA dose (p<0.001); findings were similar for streptokinase [12].
  • The majority of students reported learning about ADR and medication error reporting programs via didactic experiences [13].
  • Nurses and medication. Part 5. Medication error: the big stick to beat you with [14].
  • The NCC MERP taxonomy of medication errors is limited in mapping information from MEDWATCH because of the focus on the medical device and the format of reporting [15].
  • Interview with a quality leader: Michael Cohen on medication error reporting and patient safety. Interview by Pamela K. Scarrow and Cherrie Routon [16].


  1. Finding an optimal dose: considerations in accurate opioid dispensing. Dunn, E.B., Wolfe, J.J. Veterinary and human toxicology. (2000) [Pubmed]
  2. Lidocaine therapy with an exponentially declining infusion. Clinical evaluation of an optimized dosing technique. Sebaldt, R.J., Nattel, S., Kreeft, J.H., Ogilvie, R.I. Ann. Intern. Med. (1984) [Pubmed]
  3. Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic review. Kaushal, R., Shojania, K.G., Bates, D.W. Arch. Intern. Med. (2003) [Pubmed]
  4. Parenteral drug administration errors by nursing staff on an acute medical admissions ward during day duty. Bruce, J., Wong, I. Drug safety : an international journal of medical toxicology and drug experience. (2001) [Pubmed]
  5. Pancytopenia associated with low dose pulse methotrexate in the treatment of rheumatoid arthritis. MacKinnon, S.K., Starkebaum, G., Willkens, R.F. Semin. Arthritis Rheum. (1985) [Pubmed]
  6. Medication errors with the use of allopurinol and colchicine: a retrospective study of a national, anonymous Internet-accessible error reporting system. Mikuls, T.R., Curtis, J.R., Allison, J.J., Hicks, R.W., Saag, K.G. J. Rheumatol. (2006) [Pubmed]
  7. Case report medication error: oral antibiotics and simethicone accidentally injected intravenously. Mahne, R.C., Damen, J., Jansman, F.G. Intensive care medicine. (2003) [Pubmed]
  8. Methotrexate-associated medication errors. Harris, W. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. (2004) [Pubmed]
  9. Accidental over-anticoagulation: substitution error by a foreign pharmacy. Suwanvecho, S., Baker, J.R. The Annals of pharmacotherapy. (2000) [Pubmed]
  10. Preventing vincristine sulfate medication errors. Schulmeister, L. Oncology nursing forum. (2004) [Pubmed]
  11. Physician-pharmacist collaboration: a millennial paradigm to reduce medication errors. Sweeney, M.A. The Journal of the American Osteopathic Association. (2002) [Pubmed]
  12. Thrombolysis medication errors: benefits of bolus thrombolytic agents. Cannon, C.P. Am. J. Cardiol. (2000) [Pubmed]
  13. Adverse drug reaction and medication error reporting by pharmacy students. Sears, E.L., Generali, J.A. The Annals of pharmacotherapy. (2005) [Pubmed]
  14. Nurses and medication. Part 5. Medication error: the big stick to beat you with. Baker, H., Naphthine, R. Australian nursing journal (July 1993) (1994) [Pubmed]
  15. Evaluating a medical error taxonomy. Brixey, J., Johnson, T.R., Zhang, J. Proceedings / AMIA ... Annual Symposium. AMIA Symposium. (2002) [Pubmed]
  16. Interview with a quality leader: Michael Cohen on medication error reporting and patient safety. Interview by Pamela K. Scarrow and Cherrie Routon. Cohen, M. Journal for healthcare quality : official publication of the National Association for Healthcare Quality. (2005) [Pubmed]
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