Disease relevance of Medication Errors

• Unfortunately, medication errors associated with morphine sulfate can result in patient harm; profound respiratory depression can result from excessive doses in opioid-naïve patients [1].

High impact information on Medication Errors

• Unlike previously recommended dose regimens for lidocaine, this technique uses an exponentially declining infusion and has the advantages of greater simplicity, less chance of medication error, and avoidance of rapid changes of lidocaine concentrations [2].
• Of the 7 studies evaluating isolated CDSSs, 3 demonstrated statistically significant improvements in antibiotic-associated medication errors or adverse drug events and 1 an improvement in theophylline-associated medication errors [3].
• Very few studies have investigated the incidence of medication errors associated with parenteral drug administration [4].
• Medication errors were associated with the use of five or more medications, and the unusual schedule of administration of low dose MTX may also have been contributory [5].
• RESULTS: Gout medication errors occurred in 39% (n = 273) of facilities participating in the MEDMARX program [6].

Associations of Medication Errors with chemical compounds

• Case report medication error: oral antibiotics and simethicone accidentally injected intravenously [7].
• Methotrexate-associated medication errors [8].
• The frequency of different types of medication errors is reviewed, and problems specific to the use of warfarin are detailed [9].
• DATA SYNTHESIS: Medication errors involving vincristine sulfate include overdosage (wrong dose), name confusion (wrong drug), and incorrect administration (wrong route) [10].
• The Institute of Medicine has reported that medication errors cause an estimated 7000 deaths annually [11].

Gene context of Medication Errors

• Most importantly, 30-day mortality was significantly higher in patients with medication errors: For t-PA dosing errors, mortality was 7.7% versus 5.5% for patients who received the correct t-PA dose (p<0.001); findings were similar for streptokinase [12].
• The majority of students reported learning about ADR and medication error reporting programs via didactic experiences [13].
• Nurses and medication. Part 5. Medication error: the big stick to beat you with [14].
• The NCC MERP taxonomy of medication errors is limited in mapping information from MEDWATCH because of the focus on the medical device and the format of reporting [15].
• Interview with a quality leader: Michael Cohen on medication error reporting and patient safety. Interview by Pamela K. Scarrow and Cherrie Routon [16].

References