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Chemical Compound Review

Dalcaine     2-diethylamino-N-(2,6- dimethylphenyl)ethan...

Synonyms: Octocaine, Xylocaine, Xylocitin, lidocaine, Lignocaine, ...
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Disease relevance of Xylocitin


Psychiatry related information on Xylocitin


High impact information on Xylocitin


Chemical compound and disease context of Xylocitin


Biological context of Xylocitin


Anatomical context of Xylocitin

  • It is now thought that amine local anaesthetic compounds (procaine, lignocaine and related molecules) depress electrical activity in nerve and muscle cells by binding to sites within ion channels and blocking current flow [23].
  • Lidocaine applied topically to the left ventricle completely prevented these alterations [24].
  • Thioglycolate-stimulated mouse peritoneal macrophages cultured in the presence of macrophage growth factor (MGF) will continue to proliferate when they are removed from culture dishes with the local anesthetic lidocaine and subcultured [25].
  • However, an early lidocaine outflow peak related in time to the peak erythrocyte curve was observed in cirrhotic, but not in noncirrhotic, rats [26].
  • We speculate that this effect is due to central nervous system effects of the drug and that this effect may contribute to the antiarrhythmic actions of lidocaine [27].

Associations of Xylocitin with other chemical compounds


Gene context of Xylocitin


Analytical, diagnostic and therapeutic context of Xylocitin


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