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MeSH Review:

Complex Regional Pain Syndromes

Baron, R. et al., Hocking, G. et al., Mailis, A. et al., Maihöfner, C. et al.

Maihöfner, Forster, Birklein, Neundörfer, Handwerker,

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Disease relevance of Complex Regional Pain Syndromes

INTERPRETATION: We have shown that in complex regional pain syndromes with SMP, physiological activation of cutaneous vasoconstrictor neurons projecting to the painful arm or leg enhances spontaneous pain and hyperalgesia [1].

High impact information on Complex Regional Pain Syndromes

Relation between sympathetic vasoconstrictor activity and pain and hyperalgesia in complex regional pain syndromes: a case-control study [1].
Complex Regional Pain Syndromes (CRPS) are characterized by a triad of sensory, motor and autonomic dysfunctions of still unknown origin [2].
Effect of intravenous sodium amytal on cutaneous limb temperatures and sympathetic skin responses in normal subjects and pain patients with and without Complex Regional Pain Syndromes (type I and II). I [3].
For complex regional pain syndromes, there is only level IV evidence of efficacy of epidural ketamine [4].

References

Relation between sympathetic vasoconstrictor activity and pain and hyperalgesia in complex regional pain syndromes: a case-control study. Baron, R., Schattschneider, J., Binder, A., Siebrecht, D., Wasner, G. Lancet (2002) [Pubmed]
Brain processing during mechanical hyperalgesia in complex regional pain syndrome: a functional MRI study. Maihöfner, C., Forster, C., Birklein, F., Neundörfer, B., Handwerker, H.O. Pain (2005) [Pubmed]
Effect of intravenous sodium amytal on cutaneous limb temperatures and sympathetic skin responses in normal subjects and pain patients with and without Complex Regional Pain Syndromes (type I and II). I. Mailis, A., Plapler, P., Ashby, P., Shoichet, R., Roe, S. Pain (1997) [Pubmed]
Ketamine in chronic pain management: an evidence-based review. Hocking, G., Cousins, M.J. Anesth. Analg. (2003) [Pubmed]

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