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MeSH Review

Lupus Vasculitis, Central Nervous System

 
 
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Disease relevance of Lupus Vasculitis, Central Nervous System

  • OBJECTIVE: To determine whether volumetric magnetization transfer imaging (MTI) histogram analysis can detect abnormalities in patients with active neuropsychiatric systemic lupus erythematosus (NPSLE) and to compare the MTI findings in patients with active NPSLE, chronic NPSLE, and multiple sclerosis (MS), as well as in normal control subjects [1].
  • CSF interleukin-6 (IL-6) in patients with CNS infection (374.24 +/- 92.61 pg/mL) and neuropsychiatric systemic lupus erythematosus (NP-SLE) (71.40 +/- 5.89 pg/mL) were significantly higher than in patients with CNS inflammation (33.92 +/- 29.36 pg/mL) or controls (non-inflammatory CNS diseases) (4.35 +/- 3.00 pg/mL) [2].
 

High impact information on Lupus Vasculitis, Central Nervous System

References

  1. Detection of cerebral involvement in patients with active neuropsychiatric systemic lupus erythematosus by the use of volumetric magnetization transfer imaging. Bosma, G.P., Rood, M.J., Huizinga, T.W., de Jong, B.A., Bollen, E.L., van Buchem, M.A. Arthritis Rheum. (2000) [Pubmed]
  2. Cerebrospinal fluid interleukin-6, prostaglandin E2 and autoantibodies in patients with neuropsychiatric systemic lupus erythematosus and central nervous system infections. Tsai, C.Y., Wu, T.H., Tsai, S.T., Chen, K.H., Thajeb, P., Lin, W.M., Yu, H.S., Yu, C.L. Scand. J. Rheumatol. (1994) [Pubmed]
  3. Antibodies to microtubule-associated protein 2 in patients with neuropsychiatric systemic lupus erythematosus. Williams, R.C., Sugiura, K., Tan, E.M. Arthritis Rheum. (2004) [Pubmed]
  4. Selective gray matter damage in neuropsychiatric lupus. Steens, S.C., Admiraal-Behloul, F., Bosma, G.P., Steup-Beekman, G.M., Olofsen, H., Le Cessie, S., Huizinga, T.W., Van Buchem, M.A. Arthritis Rheum. (2004) [Pubmed]
  5. Sensitivity of quantitative (1)H magnetic resonance spectroscopy of the brain in detecting early neuronal damage in systemic lupus erythematosus. Axford, J.S., Howe, F.A., Heron, C., Griffiths, J.R. Ann. Rheum. Dis. (2001) [Pubmed]
  6. Mycophenolate mofetil in neuropsychiatric systemic lupus erythematosus. Jose, J., Paulose, B.K., Vasuki, Z., Danda, D. Indian journal of medical sciences. (2005) [Pubmed]
  7. Echolalia as a novel manifestation of neuropsychiatric systemic lupus erythematosus. Zapor, M., Murphy, F.T., Enzenauer, R. South. Med. J. (2001) [Pubmed]
 
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