Disease relevance of MAGEE1

• Two variants of the human hepatocellular carcinoma-associated HCAP1 gene and their effect on the growth of the human liver cancer cell line Hep3B [1].
• Perioperative nutritional support can reduce complications after major hepatectomy for hepatocellular carcinoma associated with cirrhosis [2].
• Hepatocellular carcinoma associated with chronic hepatitis B virus infection after kidney transplantation [3].
• A 61-yr-old woman was found to have multicentric hepatocellular carcinoma associated with clinical hyperthyroidism [4].
• A panel of six murine monoclonal antibodies against hepatocellular carcinoma-associated antigens, reactive with PLC/PRF/5 human hepatoma cells, was conjugated to Adriamycin (doxorubicin) via a dextran bridge [5].

Psychiatry related information on MAGEE1

• "Sequence Agnosia" in B??lint's Syndrome: Defects in Visuotemporal Processing after Bilateral Parietal Damage [6].
• CONCLUSIONS: Damage in the parietal and anterior cingulate cortex and posterior white matter fiber bundles correlated with hemispatial neglect [7].
• Relationship Between Vascular Damage Degrees and Endothelial Progenitor Cells in Patients with Erectile Dysfunction: Effect of Vardenafil Administration and PDE5 Expression in the Bone Marrow [8].
• Other measures that predicted an increase in the Damage Index were lower education levels, greater health locus of control attributed to chance and greater health locus of control attributed to powerful others [9].
• Oxidative Damage in Huntington's Disease Pathogenesis [10].

High impact information on MAGEE1

• DNA repair: Damage alert [11].
• The Checkpoint Clamp Activates Mec1 Kinase during Initiation of the DNA Damage Checkpoint [12].
• DNA Damage Signaling Recruits the RNA Polymerase II Binding Protein Che-1 to the p53 Promoter [13].
• A report of three multiclinic trials evaluating arbaprostil in arthritic patients with ASA/NSAID gastric mucosal damage. The Upjohn Company Arbaprostil ASA/NSAID Gastric Mucosal Damage Treatment Study Groups [14].
• The cirrhosis and hepatocellular carcinoma associated with alpha 1-antitrypsin deficiency has been exclusively reported with the PI Z allele [15].

Chemical compound and disease context of MAGEE1

• YM-244769, a Novel Na+/Ca2+ Exchange Inhibitor That Preferentially Inhibits NCX3, Efficiently Protects against Hypoxia/Reoxygenation-Induced SH-SY5Y Neuronal Cell Damage [16].
• CONCLUSIONS: Surgery and percutaneous ethanol injection improve survival in single hepatocellular carcinoma associated with Child A and B cirrhosis compared to untreated patients in the same Child class [17].
• Prevalence and correlates of left atrial enlargement in essential hypertension: role of ventricular geometry and the metabolic syndrome: the Evaluation of Target Organ Damage in Hypertension study [18].
• METHODS: We studied 261 samples, 72 with chronic hepatitis associated hepatitis C virus (HCV-CH), 57 with hepatocellular carcinoma associated HCV (HCV-HCC), 12 with HCC without either HCV or hepatitis B virus (NBNC-HCC), and 120 of BDs [19].
• The Radiation Damage Factor formula is aimed at estimating the delayed toxicity of a given treatment plan on every critical organ concerned [20].

Biological context of MAGEE1

• Experimental evidence supporting the Damage Surveillance Network model is summarized, followed by a discussion of how defects in the ATM-dependent signal transduction network might account for the A-T phenotype and what insights this new understanding of A-T can offer regarding DNA damage response networks, genomic instability, and cancer [21].
• Damage was assessed at the end of the followup period using the Systemic Lupus International Collaboration Clinics/American College of Rheumatology Damage Index [22].
• Acyl Coenzyme A-binding Protein Augments Bid-induced Mitochondrial Damage and Cell Death by Activating {micro}-Calpain [23].
• Spy1 Expression Prevents Normal Cellular Responses to DNA Damage: INHIBITION OF APOPTOSIS AND CHECKPOINT ACTIVATION [24].
• The Cell Cycle Inhibitor p21waf1 Binds to the myc and cdc25A Promoters upon DNA Damage and Induces Transcriptional Repression [25].

Anatomical context of MAGEE1

• BACKGROUND: Damage to mitochondria (mt) is a major side effect of highly active antiretroviral therapy (HAART) that includes a nucleoside reverse transcriptase inhibitor (NRTI) [26].
• In this study, we tested whether hepatocellular carcinoma thermal ablation can induce or enhance T-cell responses specific for hepatocellular carcinoma-associated antigens [27].
• To elucidate critical genetic elements in the development of hepatocellular carcinoma associated with hepatitis B virus DNA integration, a single integrant in hepatocellular carcinoma cells and one species of multiple integrants in hepatocytes, both obtained from the same patient, were compared structurally using molecular cloning techniques [28].
• Histological examination of the wall of the stomach and esophagus in patients with hepatocellular carcinoma associated with cirrhosis demonstrated intravariceal tumor thrombi in 13 (23.6%) of 55 cases studied [29].
• Interaction of human malignant melanoma (ST-ML-12) tumor spheroids with endothelial cell monolayers. Damage to endothelium by oxygen-derived free radicals [30].

Associations of MAGEE1 with chemical compounds

• Multiple Endocrine Neoplasia Type 1 Interacts with Forkhead Transcription Factor CHES1 in DNA Damage Response [31].
• Eight of 10 animals with all markers had orcein-positive inclusions (Shikata's technique) and 6 had hepatocellular carcinoma associated with acute and chronic hepatic inflammation and, usually, neoplastic nodules in the noncarcinomatous parenchyma [32].
• Loss of SLP-76 Expression within Myeloid Cells Confers Resistance to Neutrophil-Mediated Tissue Damage while Maintaining Effective Bacterial Killing [33].
• Transient Receptor Potential Vanilloid Subtype 1 Mediates Microglial Cell Death In Vivo and In Vitro via Ca2+-Mediated Mitochondrial Damage and Cytochrome c Release [34].
• Inhibitory Control is Slowed in Patients with Right Superior Medial Frontal Damage [35].

Regulatory relationships of MAGEE1

• Recruitment of the Nucleotide Excision Repair Endonuclease XPG to Sites of UV-Induced DNA Damage Depends on Functional TFIIH [36].
• DNA Damage Induces p53-dependent Down-regulation of hCHK1 [37].

Other interactions of MAGEE1

• Replication-dependent and -independent Responses of RAD18 to DNA Damage in Human Cells [38].
• Human Cytomegalovirus Disrupts both Ataxia Telangiectasia Mutated Protein (ATM)- and ATM-Rad3-Related Kinase-Mediated DNA Damage Responses during Lytic Infection [39].
• Gankyrin is a 25-kDa hepatocellular carcinoma-associated protein that mediates protein-protein interactions in cell cycle control and protein degradation [40].
• Potential involvement of the cyclooxygenase-2 pathway in hepatocellular carcinoma-associated angiogenesis [41].
• Hepatocellular carcinoma associated with hereditary hemochromatosis occurring in non-cirrhotic liver [42].

Analytical, diagnostic and therapeutic context of MAGEE1

• Treatment of hepatocellular carcinoma associated with cirrhosis in the era of liver transplantation [43].
• A prospective study is therefore warranted to elucidate whether hepatectomy or transcatheter arterial chemoembolization is more effective for treating resectable hepatocellular carcinoma associated with cirrhosis [44].
• Identical genetic material as a source for studies of cell injury. Animal model: Damage to DNA in the Amazon molly by physical and chemical agents [45].
• METHODS: In this cross-sectional study, HRQL was assessed using the Child Health Questionnaire (CHQ), disease activity using the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), and accumulated damage using the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) [46].
• The samples were coded and evaluated blindly by two pathologists, and Chronic Allograft Damage Index (CADI) score was constructed [47].

References