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Gene Review

MAGEE1  -  melanoma antigen family E, 1

Homo sapiens

Synonyms: Alpha-dystrobrevin-associated MAGE Protein, DAMAGE, HCA1, Hepatocellular carcinoma-associated protein 1, KIAA1587, ...
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Disease relevance of MAGEE1


Psychiatry related information on MAGEE1


High impact information on MAGEE1


Chemical compound and disease context of MAGEE1


Biological context of MAGEE1


Anatomical context of MAGEE1


Associations of MAGEE1 with chemical compounds


Regulatory relationships of MAGEE1


Other interactions of MAGEE1


Analytical, diagnostic and therapeutic context of MAGEE1


  1. Two variants of the human hepatocellular carcinoma-associated HCAP1 gene and their effect on the growth of the human liver cancer cell line Hep3B. Wan, D., He, M., Wang, J., Qiu, X., Zhou, W., Luo, Z., Chen, J., Gu, J. Genes Chromosomes Cancer (2004) [Pubmed]
  2. Perioperative nutritional support in patients undergoing hepatectomy for hepatocellular carcinoma. Fan, S.T., Lo, C.M., Lai, E.C., Chu, K.M., Liu, C.L., Wong, J. N. Engl. J. Med. (1994) [Pubmed]
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  4. Hepatocellular carcinoma: an unusual course with hyperthyroidism and inappropriate thyroid-stimulating hormone production. Helzberg, J.H., McPhee, M.S., Zarling, E.J., Lukert, B.P. Gastroenterology (1985) [Pubmed]
  5. Doxorubicin conjugates of monoclonal antibodies to hepatoma-associated antigens. Shouval, D., Adler, R., Wands, J.R., Hurwitz, E., Isselbacher, K.J., Sela, M. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  6. "Sequence Agnosia" in B??lint's Syndrome: Defects in Visuotemporal Processing after Bilateral Parietal Damage. Malcolm, G.L., Barton, J.J. Journal of cognitive neuroscience (2007) [Pubmed]
  7. Brain-behavior correlations in hemispatial neglect using CT and SPECT: the Sunnybrook Stroke Study. Leibovitch, F.S., Black, S.E., Caldwell, C.B., Ebert, P.L., Ehrlich, L.E., Szalai, J.P. Neurology (1998) [Pubmed]
  8. Relationship Between Vascular Damage Degrees and Endothelial Progenitor Cells in Patients with Erectile Dysfunction: Effect of Vardenafil Administration and PDE5 Expression in the Bone Marrow. Foresta, C., Caretta, N., Lana, A., De Toni, L., Biagioli, A., Vinanzi, C., Ferlin, A. Eur. Urol. (2007) [Pubmed]
  9. Time perspective predicts the progression of permanent organ damage in patients with systemic lupus erythematosus. Sundaramurthy, S., Bush, T.M., Neuwelt, C.M., Ward, M.M. Lupus (2003) [Pubmed]
  10. Oxidative Damage in Huntington's Disease Pathogenesis. Browne, S.E., Beal, M.F. Antioxid. Redox Signal. (2006) [Pubmed]
  11. DNA repair: Damage alert. Bartek, J., Lukas, J. Nature (2003) [Pubmed]
  12. The Checkpoint Clamp Activates Mec1 Kinase during Initiation of the DNA Damage Checkpoint. Majka, J., Niedziela-Majka, A., Burgers, P.M. Mol. Cell (2006) [Pubmed]
  13. DNA Damage Signaling Recruits the RNA Polymerase II Binding Protein Che-1 to the p53 Promoter. Halazonetis, T.D., Bartek, J. Mol. Cell (2006) [Pubmed]
  14. A report of three multiclinic trials evaluating arbaprostil in arthritic patients with ASA/NSAID gastric mucosal damage. The Upjohn Company Arbaprostil ASA/NSAID Gastric Mucosal Damage Treatment Study Groups. Euler, A.R., Safdi, M., Rao, J., Jaszewski, R., Welsh, J., Le, V., Raskin, J., Fleischmann, R., Razzaque, M., Champion, C. Gastroenterology (1990) [Pubmed]
  15. Diffuse hepatocellular dysplasia and carcinoma associated with the Mmalton variant of alpha 1-antitrypsin. Reid, C.L., Wiener, G.J., Cox, D.W., Richter, J.E., Geisinger, K.R. Gastroenterology (1987) [Pubmed]
  16. YM-244769, a Novel Na+/Ca2+ Exchange Inhibitor That Preferentially Inhibits NCX3, Efficiently Protects against Hypoxia/Reoxygenation-Induced SH-SY5Y Neuronal Cell Damage. Iwamoto, T., Kita, S. Mol. Pharmacol. (2006) [Pubmed]
  17. No treatment, resection and ethanol injection in hepatocellular carcinoma: a retrospective analysis of survival in 391 patients with cirrhosis. Italian Cooperative HCC Study Group. Livraghi, T., Bolondi, L., Buscarini, L., Cottone, M., Mazziotti, A., Morabito, A., Torzilli, G. J. Hepatol. (1995) [Pubmed]
  18. Prevalence and correlates of left atrial enlargement in essential hypertension: role of ventricular geometry and the metabolic syndrome: the Evaluation of Target Organ Damage in Hypertension study. Cuspidi, C., Meani, S., Fusi, V., Valerio, C., Catini, E., Sala, C., Sampieri, L., Magrini, F., Zanchetti, A. J. Hypertens. (2005) [Pubmed]
  19. High prevalance of TT virus infection in Japanese patients with liver diseases and in blood donors. Kato, T., Mizokami, M., Orito, E., Nakano, T., Tanaka, Y., Ueda, R., Hirashima, N., Iijima, Y., Kato, T., Sugauchi, F., Mukaide, M., Shimamatsu, K., Kage, M., Kojiro, M. J. Hepatol. (1999) [Pubmed]
  20. Radiotoxic model for three-dimensional treatment planning. Part 1: Theoretical basis. Caudry, M., Causse, N., Trouette, R., Récaldini, L., Maire, J.P., Demeaux, H. Int. J. Radiat. Oncol. Biol. Phys. (1993) [Pubmed]
  21. Ataxia-telangiectasia and cellular responses to DNA damage. Meyn, M.S. Cancer Res. (1995) [Pubmed]
  22. European Consensus Lupus Activity Measurement is sensitive to change in disease activity in childhood-onset systemic lupus erythematosus. Brunner, H.I., Silverman, E.D., Bombardier, C., Feldman, B.M. Arthritis Rheum. (2003) [Pubmed]
  23. Acyl Coenzyme A-binding Protein Augments Bid-induced Mitochondrial Damage and Cell Death by Activating {micro}-Calpain. Shulga, N., Pastorino, J.G. J. Biol. Chem. (2006) [Pubmed]
  24. Spy1 Expression Prevents Normal Cellular Responses to DNA Damage: INHIBITION OF APOPTOSIS AND CHECKPOINT ACTIVATION. Gastwirt, R.F., Slavin, D.A., McAndrew, C.W., Donoghue, D.J. J. Biol. Chem. (2006) [Pubmed]
  25. The Cell Cycle Inhibitor p21waf1 Binds to the myc and cdc25A Promoters upon DNA Damage and Induces Transcriptional Repression. Vigneron, A., Cherier, J., Barr??, B., Gamelin, E., Coqueret, O. J. Biol. Chem. (2006) [Pubmed]
  26. Altered mitochondrial RNA production in adipocytes from HIV-infected individuals with lipodystrophy. Galluzzi, L., Pinti, M., Guaraldi, G., Mussini, C., Troiano, L., Roat, E., Giovenzana, C., Nemes, E., Nasi, M., Orlando, G., Salomoni, P., Cossarizza, A. Antivir. Ther. (Lond.) (2005) [Pubmed]
  27. Radiofrequency thermal ablation of hepatocellular carcinoma liver nodules can activate and enhance tumor-specific T-cell responses. Zerbini, A., Pilli, M., Penna, A., Pelosi, G., Schianchi, C., Molinari, A., Schivazappa, S., Zibera, C., Fagnoni, F.F., Ferrari, C., Missale, G. Cancer Res. (2006) [Pubmed]
  28. A comparison of the molecular structure of integrated hepatitis B virus genomes in hepatocellular carcinoma cells and hepatocytes derived from the same patient. Ogata, N., Tokino, T., Kamimura, T., Asakura, H. Hepatology (1990) [Pubmed]
  29. Frequency and significance of tumor thrombi in esophageal varices in hepatocellular carcinoma associated with cirrhosis. Arakawa, M., Kage, M., Matsumoto, S., Akagi, Y., Noda, T., Fukuda, K., Nakashima, T., Okuda, K. Hepatology (1986) [Pubmed]
  30. Interaction of human malignant melanoma (ST-ML-12) tumor spheroids with endothelial cell monolayers. Damage to endothelium by oxygen-derived free radicals. Offner, F.A., Wirtz, H.C., Schiefer, J., Bigalke, I., Klosterhalfen, B., Bittinger, F., Mittermayer, C., Kirkpatrick, C.J. Am. J. Pathol. (1992) [Pubmed]
  31. Multiple Endocrine Neoplasia Type 1 Interacts with Forkhead Transcription Factor CHES1 in DNA Damage Response. Busygina, V., Kottemann, M.C., Scott, K.L., Plon, S.E., Bale, A.E. Cancer Res. (2006) [Pubmed]
  32. Woodchuck hepatitis and hepatocellular carcinoma: correlation of histologic with virologic observations. Popper, H., Shih, J.W., Gerin, J.L., Wong, D.C., Hoyer, B.H., London, W.T., Sly, D.L., Purcell, R.H. Hepatology (1981) [Pubmed]
  33. Loss of SLP-76 Expression within Myeloid Cells Confers Resistance to Neutrophil-Mediated Tissue Damage while Maintaining Effective Bacterial Killing. Clemens, R.A., Lenox, L.E., Kambayashi, T., Bezman, N., Maltzman, J.S., Nichols, K.E., Koretzky, G.A. J. Immunol. (2007) [Pubmed]
  34. Transient Receptor Potential Vanilloid Subtype 1 Mediates Microglial Cell Death In Vivo and In Vitro via Ca2+-Mediated Mitochondrial Damage and Cytochrome c Release. Kim, S.R., Kim, S.U., Oh, U., Jin, B.K. J. Immunol. (2006) [Pubmed]
  35. Inhibitory Control is Slowed in Patients with Right Superior Medial Frontal Damage. Floden, D., Stuss, D.T. Journal of cognitive neuroscience. (2006) [Pubmed]
  36. Recruitment of the Nucleotide Excision Repair Endonuclease XPG to Sites of UV-Induced DNA Damage Depends on Functional TFIIH. Zotter, A., Luijsterburg, M.S., Warmerdam, D.O., Ibrahim, S., Nigg, A., van Cappellen, W.A., Hoeijmakers, J.H., van Driel, R., Vermeulen, W., Houtsmuller, A.B. Mol. Cell. Biol. (2006) [Pubmed]
  37. DNA Damage Induces p53-dependent Down-regulation of hCHK1. Damia, G., Sanchez, Y., Erba, E., Broggini, M. J. Biol. Chem. (2001) [Pubmed]
  38. Replication-dependent and -independent Responses of RAD18 to DNA Damage in Human Cells. Nakajima, S., Lan, L., Kanno, S., Usami, N., Kobayashi, K., Mori, M., Shiomi, T., Yasui, A. J. Biol. Chem. (2006) [Pubmed]
  39. Human Cytomegalovirus Disrupts both Ataxia Telangiectasia Mutated Protein (ATM)- and ATM-Rad3-Related Kinase-Mediated DNA Damage Responses during Lytic Infection. Luo, M.H., Rosenke, K., Czornak, K., Fortunato, E.A. J. Virol. (2007) [Pubmed]
  40. The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53. Krzywda, S., Brzozowski, A.M., Higashitsuji, H., Fujita, J., Welchman, R., Dawson, S., Mayer, R.J., Wilkinson, A.J. J. Biol. Chem. (2004) [Pubmed]
  41. Potential involvement of the cyclooxygenase-2 pathway in hepatocellular carcinoma-associated angiogenesis. Zhao, Q.T., Yue, S.Q., Cui, Z., Wang, Q., Cui, X., Zhai, H.H., Zhang, L.H., Dou, K.F. Life Sci. (2007) [Pubmed]
  42. Hepatocellular carcinoma associated with hereditary hemochromatosis occurring in non-cirrhotic liver. von Delius, S., Lersch, C., Schulte-Frohlinde, E., Fend, F., Dobritz, M., Schmid, R.M., Eckel, F. Zeitschrift für Gastroenterologie. (2006) [Pubmed]
  43. Treatment of hepatocellular carcinoma associated with cirrhosis in the era of liver transplantation. Mor, E., Kaspa, R.T., Sheiner, P., Schwartz, M. Ann. Intern. Med. (1998) [Pubmed]
  44. Comparison of hepatectomy and transcatheter arterial chemoembolization for the treatment of hepatocellular carcinoma: necessity for prospective randomized trial. Yoshimi, F., Nagao, T., Inoue, S., Kawano, N., Muto, T., Gunji, T., Ohnishi, S., Imawari, M. Hepatology (1992) [Pubmed]
  45. Identical genetic material as a source for studies of cell injury. Animal model: Damage to DNA in the Amazon molly by physical and chemical agents. Setlow, R.B., Woodhead, A.D., Hart, R.W. Am. J. Pathol. (1978) [Pubmed]
  46. Health-related quality of life in juvenile-onset systemic lupus erythematosus and its relationship to disease activity and damage. Ruperto, N., Buratti, S., Duarte-Salazar, C., Pistorio, A., Reiff, A., Bernstein, B., Maldonado-Velázquez, M.R., Beristain-Manterola, R., Maeno, N., Takei, S., Falcini, F., Lepore, L., Spencer, C.H., Pratsidou-Gertsi, P., Martini, A., Ravelli, A. Arthritis Rheum. (2004) [Pubmed]
  47. Protocol core needle biopsy and histologic Chronic Allograft Damage Index (CADI) as surrogate end point for long-term graft survival in multicenter studies. Yilmaz, S., Tomlanovich, S., Mathew, T., Taskinen, E., Paavonen, T., Navarro, M., Ramos, E., Hooftman, L., Häyry, P. J. Am. Soc. Nephrol. (2003) [Pubmed]
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