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MeSH Review:

Alpharetrovirus

Hanafusa, T. et al., Tal, J. et al., Peters, G. et al., Gilbert, J.M. et al., Brojatsch, J. et al., et al.

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Disease relevance of Alpharetrovirus

The env gene of avian leukosis-sarcoma viruses encodes a glycoprotein that determines the host range and surface antigenicitiy of virions [1].
Purification of DNA complementary to the env gene of avian sarcoma virus and analysis of relationships among the env genes of avian leukosis-sarcoma viruses [1].

High impact information on Alpharetrovirus

CAR1, a TNFR-related protein, is a cellular receptor for cytopathic avian leukosis-sarcoma viruses and mediates apoptosis [2].
The pheasant viruses (PV) were similar to avian leukosis-sarcoma viruses (ALSV) in their gross morphology, in the size of their RNA, in the presence of a virion-associated RNA-dependent DNA polymerase (DNA nucleotidyltransferase; deoxynucleoside triphosphate: DNA deoxynucleotidyltransferase; EC 2.7.7.7), and in their growth characteristics [3].
The receptor for the subgroup A avian leukosis-sarcoma viruses binds to subgroup A but not to subgroup C envelope glycoprotein [4].
In most respects, the interaction between primer and template in Moloney murine leukemia virus parallels the situation in the avian leukosis-sarcoma viruses [5].
Deletion of a Cys-His motif from the Alpharetrovirus nucleocapsid domain reveals late domain mutant-like budding defects [6].

Analytical, diagnostic and therapeutic context of Alpharetrovirus

Radioimmunoassay for the envelope glycoprotein of subgroup E avian leukosis-sarcoma viruses [7].

References

Purification of DNA complementary to the env gene of avian sarcoma virus and analysis of relationships among the env genes of avian leukosis-sarcoma viruses. Tal, J., Fujita, D.J., Kawai, S., Varmus, H.E., Bishop, J.M. J. Virol. (1977) [Pubmed]
CAR1, a TNFR-related protein, is a cellular receptor for cytopathic avian leukosis-sarcoma viruses and mediates apoptosis. Brojatsch, J., Naughton, J., Rolls, M.M., Zingler, K., Young, J.A. Cell (1996) [Pubmed]
Pheasant virus: new class of ribodeoxyvirus. Hanafusa, T., Hanafusa, H., Metroka, C.E., Hayward, W.S., Rettenmier, C.W., Sawyer, R.C., Dougherty, R.M., Distefano, H.S. Proc. Natl. Acad. Sci. U.S.A. (1976) [Pubmed]
The receptor for the subgroup A avian leukosis-sarcoma viruses binds to subgroup A but not to subgroup C envelope glycoprotein. Gilbert, J.M., Bates, P., Varmus, H.E., White, J.M. J. Virol. (1994) [Pubmed]
RNA-directed DNA synthesis in Moloney murine leukemia virus: interaction between the primer tRNA and the genome RNA. Peters, G., Dahlberg, J.E. J. Virol. (1979) [Pubmed]
Deletion of a Cys-His motif from the Alpharetrovirus nucleocapsid domain reveals late domain mutant-like budding defects. Lee, E.G., Linial, M.L. Virology (2006) [Pubmed]
Radioimmunoassay for the envelope glycoprotein of subgroup E avian leukosis-sarcoma viruses. Smith, E.J., Crittenden, L.B., Whitson, A.K. Virology (1978) [Pubmed]

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