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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Parechovirus

  • Here, we demonstrate that the replication of parechovirus 1 (ParV1) is partly resistant to BFA, whereas echovirus 11 (EV11) replication is strongly inhibited [1].
  • To study humoral and cellular immunity against human parechovirus type 1 (HPEV1), the viral capsid proteins VP0, VP1, and VP3 were expressed and purified as glutathione S-transferase (GST)-tagged recombinant proteins [2].

High impact information on Parechovirus


  1. Differential requirements for COPI coats in formation of replication complexes among three genera of Picornaviridae. Gazina, E.V., Mackenzie, J.M., Gorrell, R.J., Anderson, D.A. J. Virol. (2002) [Pubmed]
  2. Diagnostic potential of parechovirus capsid proteins. Alho, A., Marttila, J., Ilonen, J., Hyypiä, T. J. Clin. Microbiol. (2003) [Pubmed]
  3. ATP hydrolysis and AMP kinase activities of nonstructural protein 2C of human parechovirus 1. Samuilova, O., Krogerus, C., Fabrichniy, I., Hyypiä, T. J. Virol. (2006) [Pubmed]
  4. Terminal RNA replication elements in human parechovirus 1. Nateri, A.S., Hughes, P.J., Stanway, G. J. Virol. (2002) [Pubmed]
  5. TLR8 and TLR7 are involved in the host's immune response to human parechovirus 1. Triantafilou, K., Vakakis, E., Orthopoulos, G., Ahmed, M.A., Schumann, C., Lepper, P.M., Triantafilou, M. Eur. J. Immunol. (2005) [Pubmed]
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