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MeSH Review

Primula

 
 
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Disease relevance of Primula

  • After chromatographic separation of the test substance on a small Sephadex G 25 column, ECF was demonstrated in blisters of five patients with bullous pemphigoid, in three patients with systemic drug reactions and in one patient with blisters are contact with primula [1].
  • First, to determine whether the incidence of primula allergic contact dermatitis was truly on the decline and, second, to confirm the presence of primin-free P. obconica in the UK [2].
 

High impact information on Primula

 

Associations of Primula with chemical compounds

References

  1. Eosinophil chemotactic factor (ECF) in blister fluid of dermatological diseases. Dierksmeier, U., Frosch, P.J., Czarnetzki, B.M. Br. J. Dermatol. (1980) [Pubmed]
  2. Primula obconica--is contact allergy on the decline? Connolly, M., Mc Cune, J., Dauncey, E., Lovell, C.R. Contact Derm. (2004) [Pubmed]
  3. Analysis of phenolic glycosides and saponins in Primulaelatior and Primulaveris (primula root) by liquid chromatography, evaporative light scattering detection and mass spectrometry. Müller, A., Ganzera, M., Stuppner, H. Journal of chromatography. A. (2006) [Pubmed]
  4. Allergic contact dermatitis from primula presenting as vitiligo. Bhushan, M., Beck, M.H. Contact Derm. (1999) [Pubmed]
  5. 2-methoxy-6-pentyl-1,4-dihydroxybenzene (miconidin) from Primula obconica: a possible allergen? Krebs, M., Christensen, L.P. Contact Derm. (1995) [Pubmed]
  6. Macrophyllicin, a saponin from Primula macrophylla. Ahmad, V.U., Shah, M.G., Mohammad, F.V., Baqai, F.T. Phytochemistry (1993) [Pubmed]
  7. Primin-free Primula obconica plants available. Christensen, L.P., Larsen, E. Contact Derm. (2000) [Pubmed]
  8. The sensitizing capacity of naturally occurring quinones. Experimental studies in guinea pigs. II. Benzoquinones. Schulz, K.H., Garbe, I., Hausen, B.M., Simatupang, M.H. Arch. Dermatol. Res. (1979) [Pubmed]
  9. 5,8-dihydroxyflavone (primetin) the contact sensitizer of Primula mistassinica Michaux. Hausen, B.M., Schmalle, H.W., Marshall, D., Thomson, R.H. Arch. Dermatol. Res. (1983) [Pubmed]
 
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