High impact information on Methanobrevibacter

• Sequence alignment of the phosphoribosylaminoimidazole carboxylase heterodimer from B. subtilis with the monomeric enzyme from Methanobrevibacter smithii indicates an evolutionary relationship between these two enzymes [1].
• A diphytanyl ether analog of phosphatidylserine from a methanogenic bacterium, Methanobrevibacter arboriphilus [2].
• We have previously cloned and sequenced a purE-complementing gene from the mesophilic methanogen Methanobrevibacter smithii [3].
• Characterization of a heme-dependent catalase from Methanobrevibacter arboriphilus [4].
• One of these bacteria reacted with antiserum against Methanobrevibacter arboriphilus AZ, whereas the other is most likely a propionate-oxidizing bacterium immunologically unrelated to Syntrophobacter wolinii [5].

Associations of Methanobrevibacter with chemical compounds

• Evidence for a nickel-containing carbon monoxide dehydrogenase in Methanobrevibacter arboriphilicus [6].
• This was supported by the structural elucidation of the methanofuran isolated from Methanobrevibacter smithii, designated methanofuran-c, which was the same as the originally characterized methanofuran except for a hydroxy group at the 2 position of the 4,5-dicarboxyoctanedioic acid moiety of the molecule [7].
• To test this hypothesis Methanobrevibacter ruminantium, which requires coenzyme M as a vitamin, was grown in the presence of [2-14C]CoMSH [8].
• F420H2 oxidase (FprA) from Methanobrevibacter arboriphilus, a coenzyme F420-dependent enzyme involved in O2 detoxification [9].
• Approximately 4 nmol of lovastatin per milliliter resulted in 50% growth inhibition of Methanobrevibacter strain ZA10 and concentrations > or =10 nmol per milliliter completely inhibited growth and CH4 formation [10].

References