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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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High impact information on Spondylolysis


Chemical compound and disease context of Spondylolysis

  • Seven patients had spondylolysis at C6 (three bilateral) and five had the abnormality at C4 (all unilateral) [6].

Gene context of Spondylolysis

  • Our findings illustrate that nonpenetrance for the typical features of BDC can be appreciable and that atypical skeletal features that have been reported in some patients with BDC (i.e., clubfoot, short stature, spondylolysis) may also result from CDMP-1 mutation [7].
  • 99Tcm MDP bone scans were performed in three patients, in whom 4 of 5 spondylolyses were shown to have a high uptake [8].
  • The Cohen Kappa ratio of 0.362 (95% CI: 0.198-0.526) suggests only fair agreement for the result of increased scintigraphic activity with the finding of spondylolysis on rg-CT [9].
  • The association of these cysts with trauma, rheumatoid arthritis, spondylolysis, and kissing spinous processes also has been reported [10].


  1. Case 36: bilateral cervical spondylolysis of C6. Schwartz, J.M. Radiology. (2001) [Pubmed]
  2. Early diagnosis of disc-space infection using Gallium-67. Norris, S., Ehrlich, M.G., Keim, D.E., Guiterman, H., McKusick, K.A. J. Nucl. Med. (1978) [Pubmed]
  3. The nature of the spondylolytic defect. Demonstration of a communicating synovial pseudarthrosis in the pars interarticularis. Shipley, J.A., Beukes, C.A. The Journal of bone and joint surgery. British volume. (1998) [Pubmed]
  4. Early diagnosis of lumbar spondylolysis by MRI. Yamane, T., Yoshida, T., Mimatsu, K. The Journal of bone and joint surgery. British volume. (1993) [Pubmed]
  5. Spondylolysis of C2: CT and plain film findings. Kish, K.K., Wilner, H.I. Journal of computer assisted tomography. (1983) [Pubmed]
  6. Cervical spondylolysis: imaging findings in 12 patients. Forsberg, D.A., Martinez, S., Vogler, J.B., Wiener, M.D. AJR. American journal of roentgenology. (1990) [Pubmed]
  7. Broad phenotypic spectrum caused by an identical heterozygous CDMP-1 mutation in three unrelated families. Savarirayan, R., White, S.M., Goodman, F.R., Graham, J.M., Delatycki, M.B., Lachman, R.S., Rimoin, D.L., Everman, D.B., Warman, M.L. Am. J. Med. Genet. A (2003) [Pubmed]
  8. Review of spondylolisthesis and spondylolysis in paediatric practice. Oakley, R.H., Carty, H. The British journal of radiology. (1984) [Pubmed]
  9. The value of combining single photon emission computerised tomography and computerised tomography in the investigation of spondylolysis. Gregory, P.L., Batt, M.E., Kerslake, R.W., Scammell, B.E., Webb, J.F. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. (2004) [Pubmed]
  10. Bilateral symptomatic synovial cysts of the lumbar spine caused by calcium pyrophosphate deposition disease: a case report. Gadgil, A.A., Eisenstein, S.M., Darby, A., Cassar Pullicino, V. Spine. (2002) [Pubmed]
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