Disease relevance of gallium

• Each person in the study was examined by gallium-67 scanning for a general estimate of pulmonary inflammation, and by bronchoalveolar lavage for characterization of the types of recovered cells and their state of activation [1].
• Gallium 67 scans in small cell carcinoma [2].
• Empyema seven years after pneumonectomy. Detection by Gallium 67 scan [3].
• This study was designed to evaluate the applicability of gallium-67 (67Ga) myocardial imaging as an adjunct to endomyocardial biopsy in the diagnosis of myocarditis [4].
• Twenty control patients without cardiac disease had negative gallium-67 scans [5].

Psychiatry related information on gallium

• Comparison of bone and gallium-67 imaging in heroin users' arthritis [6].
• Gallium-67 whole body images correlated well with the clinical course of the disease and with the patient's prognosis [7].
• Gallium-67 detection of intramammary injection sites secondary to intravenous drug abuse [8].

High impact information on gallium

• Common pathway for tumor cell uptake of gallium-67 and iron-59 via a transferrin receptor [9].
• Muscles undergoing physiological adaptation to stress take up gallium-67 citrate [10].
• Gallium-67 imaging in cardiomyopathy [11].
• We conclude that gallium-67 myocardial scintigraphy may be a useful test for predicting the response to prednisone and azathioprine therapy [5].
• Utility of gallium-67 scintigraphy in low-grade non-Hodgkin's lymphoma [12].

Chemical compound and disease context of gallium

• We have studied gallium-67 citrate scan (Ga-67) in the diagnosis of lymphadenopathy in patients with HIV-associated symptoms [13].
• Fluorine-18 fluorodeoxyglucose positron emission tomography, gallium-67 scintigraphy, and conventional staging for Hodgkin's disease and non-Hodgkin's lymphoma [14].
• Thallium-201 scintigraphy for assessment of a gallium-67-avid mediastinal mass following therapy for Hodgkin's disease [15].
• Gallium-67 in the evaluation of sarcoidosis: correlations with serum angiotensin-converting enzyme and bronchoalveolar lavage [16].
• Eighteen patients with multiple myeloma were studied using radiographs of the skeletal system, technetium phosphate bone scans, and gallium-67 scintigraphy [17].

Biological context of gallium

• We conclude that abnormal mediastinal gallium-67 uptake after completion of chemotherapy is likely to be benign and transient if the patients are young, have small non-cleaved-cell histology, are without other evidence of lymphoma recurrence, and do not have initial mediastinal involvement [18].
• Difference in gallium-67 tissue distribution in male and female mice [19].
• Gallium-67 has been a controversial tumor-imaging agent in nuclear medicine for decades [20].
• Lavage cell counts, serum angiotensin converting enzyme (SACE) determinations, and gallium-67 scans were planned at standard intervals but were not used in management decisions [21].
• Role of iron-binding proteins and enhanced capillary permeability on the accumulation of gallium-67 [22].

Anatomical context of gallium

• We observed increased gallium-67 uptake in the mediastinum after completion of chemotherapy in 10 of 62 patients with non-Hodgkin's lymphoma [18].
• PATIENTS AND METHODS: All patients had MRI, gallium-67 single-photon emission CT (67Ga SPECT), and erythrocyte sedimentation rate (ESR) performed within 3 months of completing therapy [23].
• Gallium-67 scan for distinguishing follicular hyperplasia from other AIDS-associated diseases in lymph nodes [13].
• The purpose of this study was to assess the frequency of inflammatory lesions in the myocardium of subjects with dilated cardiomyopathy and to determine if there was any correlation between the results of two methods of evaluation, one (endomyocardial biopsy) invasive and the other (gallium-67 scintigraphy) noninvasive [24].
• Gallium-67 imaging, performed 48 hr after the leukocyte studies, revealed multiple areas of abnormal radiotracer accumulation corresponding to regions of active sarcoid in both women [25].

Associations of gallium with other chemical compounds

• A gallium-67/technetium-99m subtraction technique was used with a variable weighting factor [26].
• Will thallium-201 replace gallium-67 in salivary gland scintigraphy [27]?
• Role of phosphate-containing compounds in the transfer of indium-111 and gallium-67 from transferrin to ferritin [28].
• The effect of methylene diphosphonate on the tissue distribution of gallium-67 [29].
• Intramuscular injection of histamine caused accumulation of gallium-67 (injected i.v. as citrate), and of Tc-99m DTPA, at the i.m. injection site [22].

Gene context of gallium

• Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin-independent mechanisms [30].
• Patients with positive gallium-67 uptake or bilateral hilar lymphadenopathy had high levels of either serum IFN-gamma or lysozyme [31].
• The patients positive for gallium-67 ((67)Ga) scan had significantly elevated serum IL-18 levels as compared with those of the negative patients [32].
• Gallium-67/gallium-68-[DFO]-octreotide--a potential radiopharmaceutical for PET imaging of somatostatin receptor-positive tumors: synthesis and radiolabeling in vitro and preliminary in vivo studies [33].
• In one patient, a lesion in the femur, which was detected by computed tomography (CT) and gallium-67 scans, was also seen on the CD19 scan from 1 h after administration of the radioimmunoconjugate onwards [34].

Analytical, diagnostic and therapeutic context of gallium

• The interval between cessation of chemotherapy and the development of increased gallium-67 uptake ranged from 1 to 8 months, and the abnormality persisted for 2 to 59 months [18].
• Gallium-67 could not detect tumor response early after treatment, but showed a marked change in uptake later [35].
• Their clinical and radiographic findings and results of pulmonary function tests, gallium-67 lung scanning, and cellular analysis of bronchoalveolar lavage fluid were compared at diagnosis [36].
• Comparison of computed tomography, ultrasonography, and gallium-67 scanning in the evaluation of suspected abdominal abscess [37].
• Early diagnosis of disc-space infection using Gallium-67 [38].

References