Disease relevance of Spinal Cord Compression

• Situs inversus and compressive myelopathy in Klippel Feil syndrome [1].

High impact information on Spinal Cord Compression

• 8. These findings demonstrate that U74006F can significantly protect locomotor function in our model of compression spinal cord injury if administered as late as 4 hours postinjury [2].
• The results provided the risk factor for predicting compressive myelopathy due to lower cervical spine lesions in patients with rheumatoid arthritis [3].
• OBJECT: The authors conducted a study to examine whether high-resolution [18F]fluorodeoxyglucose (FDG)-positron emission tomography (PET) could be used to visualize deterioration of cervical spinal cord function associated with various degrees of compression and to determine its potential usefulness during assessment of compressive myelopathy [4].
• The present authors hypothesized that there existed an increased expression of NF proteins and GAP-43 in twy/twy mice during the lengthy period of spinal cord compression, which resembles compressive myelopathy [5].
• Ossification of the posterior longitudinal ligament (OPLL) is an uncommon cause of compressive myelopathy outside Japan. A case of cervical cord compression in a female whose MRI showed OPLL is reported [6].

Gene context of Spinal Cord Compression

• A calcified central sequestrated disc is the only condition that may be mistaken for the segmental and retrodiscal forms of OPLL In a clinical setting of compressive myelopathy, it is pertinent to distinguish between these two conditions since a sequestrated disc has a more favourable surgical prognosis [7].

References