- Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth. Brun, S., Carmona, M.C., Mampel, T., Viñas, O., Giralt, M., Iglesias, R., Villarroya, F. Diabetes (1999)