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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

An unusual case of hypoxia from benzocaine-induced methemoglobinemia.

Hypoxemia during bronchoscopy occurs frequently. It can usually be managed by supplemental oxygen and bronchodilators or, in some cases, occasionally stopping the procedure. Benzocaine spray is commonly used as a topical anesthetic agent during bronchoscopy. However, it has been associated with the development of methemoglobinemia. The following is a case report of hypoxia during bronchoscopy from benzocaine-induced methemoglobinemia and its management.[1]


  1. An unusual case of hypoxia from benzocaine-induced methemoglobinemia. Slaughter, M.S., Gordon, P.J., Roberts, J.C., Pappas, P.S. Ann. Thorac. Surg. (1999) [Pubmed]
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