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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Schmitz, F.J. et al.

Schmitz, Petridou, Fluit, Hadding, Peters, von Eiff,

Distribution of macrolide-resistance genes in Staphylococcus aureus blood-culture isolates from fifteen German university hospitals. M.A.R.S. Study Group. Multicentre Study on Antibiotic Resistance in Staphylococci.

The purpose of the study was to analyze the distribution of the macrolide-resistance genes in 134 erythromycin-resistant Staphylococcus aureus blood-culture isolates collected at 15 German university hospitals. The most prevalent resistance gene was ermC (68/134; 50.7%), followed by ermA (52/134; 38.8%), ereB (10/134; 7.5%), and mrsA/msrB (4/134; 6%). The least common genes were ermB (3/134; 2.2%) and ereA (1/134; 0.7%). Overall, resistance to erythromycin was predominantly due to the presence of two erm genes, although with different distributions, depending on the methicillin-resistance pattern.[1]

References

Distribution of macrolide-resistance genes in Staphylococcus aureus blood-culture isolates from fifteen German university hospitals. M.A.R.S. Study Group. Multicentre Study on Antibiotic Resistance in Staphylococci. Schmitz, F.J., Petridou, J., Fluit, A.C., Hadding, U., Peters, G., von Eiff, C. Eur. J. Clin. Microbiol. Infect. Dis. (2000) [Pubmed]

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