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Wormley, F.L. et al.

Resistance of T-cell receptor delta-chain-deficient mice to experimental Candida albicans vaginitis.

Conditions consistent with tolerance or immunoregulation have been observed in experimental Candida albicans vaginal infections. The present study investigated the role of gamma/delta T cells in experimental vaginal candidiasis. Results showed that T-cell receptor delta-chain-knockout mice had significantly less vaginal fungal burden when compared to wild-type mice, suggesting an immunoregulatory role for gamma/delta T cells in Candida vaginitis.[1]

References

Resistance of T-cell receptor delta-chain-deficient mice to experimental Candida albicans vaginitis. Wormley, F.L., Steele, C., Wozniak, K., Fujihashi, K., McGhee, J.R., Fidel, P.L. Infect. Immun. (2001) [Pubmed]

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