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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The comparative efficacy of diamphenethide and rafoxanide against fasciola gigantica in sheep.

Efficacy of diamphenethide ("Coriban", Burroughs Wellcome) and rafoxanide ("Ranide", Merck Sharpe & Dohme, Ltd.) was evaluated in lambs against 8-week old experimentally induced Fasciola gigantica infection. Results were assessed by the reduction in worm counts at post-mortem examination 8 weeks after treatment. Diamphenethide at a dosage rate of 100 mg/kg body weight was found 99.4 per cent effective. Rafoxanide at a dosage rate of 10 mg/kg body weight showed 98.78 per cent efficacy. Six weeks following treatment, infected animals treated with either drug exhibited significantly greater weight gain than the non-treated infected animals.[1]

References

  1. The comparative efficacy of diamphenethide and rafoxanide against fasciola gigantica in sheep. Kadhim, J.K. Tropenmedizin und Parasitologie. (1975) [Pubmed]
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