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Disease relevance of Fasciola


High impact information on Fasciola


Chemical compound and disease context of Fasciola


Biological context of Fasciola


Anatomical context of Fasciola


Associations of Fasciola with chemical compounds


Gene context of Fasciola


Analytical, diagnostic and therapeutic context of Fasciola


  1. Gene cloning, overproduction and purification of a functionally active cytoplasmic fatty acid-binding protein (Sj-FABPC) from the human blood fluke Schistosoma japonicum. Becker, M.M., Kalinna, B.H., Waine, G.J., McManus, D.P. Gene (1994) [Pubmed]
  2. Proline in fascioliasis: III. Activities of pyrroline-5-carboxylic acid reductase and pyrroline-5-carboxylic acid dehydrogenase in Fasciola. Isseroff, H., Ertel, J.C. Int. J. Parasitol. (1976) [Pubmed]
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  6. Chemotherapy of parasitic worms: new biochemical strategies. Mansour, T.E. Science (1979) [Pubmed]
  7. Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells. Collins, P.R., Stack, C.M., O'Neill, S.M., Doyle, S., Ryan, T., Brennan, G.P., Mousley, A., Stewart, M., Maule, A.G., Dalton, J.P., Donnelly, S. J. Biol. Chem. (2004) [Pubmed]
  8. RNA trans-splicing in Fasciola hepatica. Identification of a spliced leader (SL) RNA and SL sequences on mRNAs. Davis, R.E., Singh, H., Botka, C., Hardwick, C., Ashraf el Meanawy, M., Villanueva, J. J. Biol. Chem. (1994) [Pubmed]
  9. Vaccination of sheep against Fasciola hepatica with glutathione S-transferase. Identification and mapping of antibody epitopes on a three-dimensional model of the antigen. Sexton, J.L., Wilce, M.C., Colin, T., Wijffels, G.L., Salvatore, L., Feil, S., Parker, M.W., Spithill, T.W., Morrison, C.A. J. Immunol. (1994) [Pubmed]
  10. Serotonin-activated adenylate cyclase from Fasciola hepatica. Properties of the solubilized enzyme. Northup, J.K., Renart, M.F., Grove, J.R., Mansour, T.E. J. Biol. Chem. (1979) [Pubmed]
  11. Immunodiagnosis of Fasciola hepatica infection (fascioliasis) in a human population in the Bolivian Altiplano using purified cathepsin L cysteine proteinase. O'Neill, S.M., Parkinson, M., Strauss, W., Angles, R., Dalton, J.P. Am. J. Trop. Med. Hyg. (1998) [Pubmed]
  12. Differential inhibition of rat hepatic glutathione S-transferase isoenzymes in the course of fascioliasis. Galtier, P., Vandenberghe, Y., Coecke, S., Eeckhoutte, C., Larrieu, G., Vercruysse, A. Mol. Biochem. Parasitol. (1991) [Pubmed]
  13. Peripheral androgen levels in peripuberal rams infected with Fasciola hepatica. Fleming, M.W., Fetterer, R.H. Vet. Parasitol. (1986) [Pubmed]
  14. Toxicity of fluometuron and diuron on the intermediate snail host (Lymnea spp.) of Fasciola hepatica. Christian, F.A., Tate, T.M. Bulletin of environmental contamination and toxicology. (1983) [Pubmed]
  15. Fascioliasis of livestock and snail host for Fasciola in the Altiplano Region of Bolivia. Ueno, H., Arandia, R., Morales, G., Medina, G. National Institute of Animal Health quarterly. (1975) [Pubmed]
  16. The in vivo effects of rafoxanide on the energy metabolism of Fasciola hepatica. Cornish, R.A., Behm, C.A., Butler, R.W., Bryant, C. Int. J. Parasitol. (1977) [Pubmed]
  17. Cloning of a protease gene family of Fasciola hepatica by the polymerase chain reaction. Heussler, V.T., Dobbelaere, D.A. Mol. Biochem. Parasitol. (1994) [Pubmed]
  18. Developmental expression of a Fasciola hepatica sequence homologous to ABC transporters. Reed, M.B., Panaccio, M., Strugnell, R.A., Spithill, T.W. Int. J. Parasitol. (1998) [Pubmed]
  19. Cell mediated immunity to liver fluke antigens during experimental Fasciola hepatica infection of cattle. Oldham, G., Williams, L. Parasite Immunol. (1985) [Pubmed]
  20. The identification of a Clonorchis sinensis gene encoding an antigenic egg protein. Lee, M., Chung, Y.B., Lee, S.K., Chung, B.S., Li, S., Choi, M.H., Hong, S.T. Parasitol. Res. (2005) [Pubmed]
  21. Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages. Donnelly, S., O'Neill, S.M., Sekiya, M., Mulcahy, G., Dalton, J.P. Infect. Immun. (2005) [Pubmed]
  22. Temporal and spatial increase of astroglial basic fibroblast growth factor synthesis after 6-hydroxydopamine-induced degeneration of the nigrostriatal dopamine neurons. Chadi, G., Cao, Y., Pettersson, R.F., Fuxe, K. Neuroscience (1994) [Pubmed]
  23. Pharmacological profile of the 5-hydroxytryptamine receptor of Fasciola hepatica body wall muscle. Tembe, E.A., Holden-Dye, L., Smith, S.W., Jacques, P.A., Walker, R.J. Parasitology (1993) [Pubmed]
  24. Reduced serotonergic immunoreactive fibers in the forebrain of alcohol-preferring rats. Zhou, F.C., Bledsoe, S., Lumeng, L., Li, T.K. Alcohol. Clin. Exp. Res. (1994) [Pubmed]
  25. Distribution of bismuth in the brain after intraperitoneal dosing of bismuth subnitrate in mice: implications for routes of entry of xenobiotic metals into the brain. Ross, J.F., Switzer, R.C., Poston, M.R., Lawhorn, G.T. Brain Res. (1996) [Pubmed]
  26. Adenosine cyclic 3',5'-monophosphate in the liver fluke, Fasciola hepatica. II. Activation of protein kinase by 5-hydroxytryptamine. Gentleman, S., Abrahams, S.L., Mansour, T.E. Mol. Pharmacol. (1976) [Pubmed]
  27. The secreted cathepsin L-like proteinases of the trematode, Fasciola hepatica, contain 3-hydroxyproline residues. Wijffels, G.L., Panaccio, M., Salvatore, L., Wilson, L., Walker, I.D., Spithill, T.W. Biochem. J. (1994) [Pubmed]
  28. Presclerotized eggshell protein from the liver fluke Fasciola hepatica. Waite, J.H., Rice-Ficht, A.C. Biochemistry (1987) [Pubmed]
  29. A histidine-rich protein from the vitellaria of the liver fluke Fasciola hepatica. Waite, J.H., Rice-Ficht, A.C. Biochemistry (1989) [Pubmed]
  30. Imported Fasciola hepatica infection in the United States and treatment with triclabendazole. Graham, C.S., Brodie, S.B., Weller, P.F. Clin. Infect. Dis. (2001) [Pubmed]
  31. Mucin-type O-glycosylation in Fasciola hepatica: characterisation of carcinoma-associated Tn and sialyl-Tn antigens and evaluation of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity. Freire, T., Casaravilla, C., Carmona, C., Osinaga, E. Int. J. Parasitol. (2003) [Pubmed]
  32. Expression of interleukin 4, interleukin 4 splice variants and interferon gamma mRNA in calves experimentally infected with Fasciola hepatica. Waldvogel, A.S., Lepage, M.F., Zakher, A., Reichel, M.P., Eicher, R., Heussler, V.T. Vet. Immunol. Immunopathol. (2004) [Pubmed]
  33. Identification of enolase as a plasminogen-binding protein in excretory-secretory products of Fasciola hepatica. Bernal, D., de la Rubia, J.E., Carrasco-Abad, A.M., Toledo, R., Mas-Coma, S., Marcilla, A. FEBS Lett. (2004) [Pubmed]
  34. Development of detection methods for ruminant interleukin (IL)-4. Hope, J.C., Kwong, L.S., Thom, M., Sopp, P., Mwangi, W., Brown, W.C., Palmer, G.H., Wattegedera, S., Entrican, G., Howard, C.J. J. Immunol. Methods (2005) [Pubmed]
  35. Acyl-CoA transferase activities in homogenates of Fasciola hepatica adults. Saz, H.J., deBruyn, B., de Mata, Z. J. Parasitol. (1996) [Pubmed]
  36. Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase. Rossjohn, J., Feil, S.C., Wilce, M.C., Sexton, J.L., Spithill, T.W., Parker, M.W. J. Mol. Biol. (1997) [Pubmed]
  37. Molecular cloning and expression of Cu/Zn-containing superoxide dismutase from Fasciola hepatica. Kim, T.S., Jung, Y., Na, B.K., Kim, K.S., Chung, P.R. Infect. Immun. (2000) [Pubmed]
  38. Serodiagnosis of human fascioliasis by a cystatin capture enzyme-linked immunosorbent assay with recombinant Fasciola gigantica cathepsin L antigen. Tantrawatpan, C., Maleewong, W., Wongkham, C., Wongkham, S., Intapan, P.M., Nakashima, K. Am. J. Trop. Med. Hyg. (2005) [Pubmed]
  39. Mechanism of inactivation of a Fasciola proteolytic enzyme by peptide aldehydes and alkylating agents. Aoki, T., Yamasaki, H., Oya, H. Mol. Biochem. Parasitol. (1983) [Pubmed]
  40. The effect of diamphenethide on protein synthesis by the liver fluke, Fasciola hepatica. Anderson, H.R., Fairweather, I., Bamford, D.R., Montgomery, W.I. Int. J. Parasitol. (1993) [Pubmed]
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