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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Body mass index and quality of life in community-dwelling patients with schizophrenia.

OBJECTIVE: To examine the associations between sociodemographic variables, body weight and quality of life in schizophrenic outpatients. METHODS: Assessments included an interview to obtain sociodemographic data, administration of a Quality of Life questionnaire (the MOS SF-36) and measurement of height and weight. Body mass index was calculated (kg/m(2)). SF-36 subscores were examined for statistical differences based on BMI categories: healthy weight (BMI<or=24.9), overweight (BMI 25-29.9) and obese (BMI>or=30). Correlations with sociodemographic variables were also examined. RESULTS: Body weight was inversely correlated (level p<or=0.005) to the SF-36 items: physical functioning (PF, -0.452), role limitations due to physical functioning (-0.279), role limitations due to emotional functioning (-0.256), vitality (-0.200), general health (GH, -0.367) and physical component score ( PCS, -0.400). Mental component score ( MCS) was not significantly correlated to body weight. When comparing quality of life across BMI categories, obese subjects had worse physical functioning (p<or=0.0005) and general health (p<or=0.005), reported more role limitations due to emotional functioning (p<or=0.05) and a lower physical component score (p<or=0.005). Mental component score was not significantly influenced by BMI. CONCLUSIONS: Quality of life in schizophrenic patients is related to body weight. The burden of obesity is primarily experienced as a physical problem.[1]

References

  1. Body mass index and quality of life in community-dwelling patients with schizophrenia. Strassnig, M., Brar, J.S., Ganguli, R. Schizophr. Res. (2003) [Pubmed]
 
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