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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

cDNA sequence for rat dermatan sulfate proteoglycan-II ( decorin).

A cDNA clone for dermatan sulfate proteoglycan-II, or decorin, has been isolated from a rat uterus library and sequenced. The cDNA and deduced amino acid sequences are 79 and 77% identical to the previously reported human and bovine sequences, respectively. The rat protein contains potential attachment sites for two glycosaminoglycan chains and four N-linked oligosaccharides, six conserved cysteine residues and multiple repeats of a leucine-rich sequence, LXXLXLXXNXL/I. Overlapping the C-end of one of these repeats is an NKISK sequence, which has been implicated in binding to fibronectin.[1]


  1. cDNA sequence for rat dermatan sulfate proteoglycan-II (decorin). Abramson, S.R., Woessner, J.F. Biochim. Biophys. Acta (1992) [Pubmed]
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