- In vivo treatment with a monoclonal antibody to interferon-gamma neither affects the survival nor the incidence of lupus-nephritis in the MRL/lpr-lpr mouse. Nicoletti, F., Meroni, P., Di Marco, R., Barcellini, W., Borghi, M.O., Gariglio, M., Mattina, A., Grasso, S., Landolfo, S. Immunopharmacology (1992)