- FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells. Imai, T., Adachi, S., Nishijo, K., Ohgushi, M., Okada, M., Yasumi, T., Watanabe, K., Nishikomori, R., Nakayama, T., Yonehara, S., Toguchida, J., Nakahata, T. Oncogene (2003)