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Isakbaeva, E.T. et al.

Isakbaeva, Khetsuriani, Beard, Peck, Erdman, Monroe, Tong, Ksiazek, Lowther, Pandya-Smith, Anderson, Lingappa, Widdowson,

SARS-associated coronavirus transmission, United States.

To better assess the risk for transmission of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV), we obtained serial specimens and clinical and exposure data from seven confirmed U.S. SARS patients and their 10 household contacts. SARS-CoV was detected in a day-14 sputum specimen from one case-patient and in five stool specimens from two case-patients. In one case-patient, SARS-CoV persisted in stool for at least 26 days after symptom onset. The highest amounts of virus were in the day-14 sputum sample and a day-14 stool sample. Residual respiratory symptoms were still present in recovered SARS case-patients 2 months after illness onset. Possible transmission of SARS-CoV occurred in one household contact, but this person had also traveled to a SARS-affected area. The data suggest that SARS-CoV is not always transmitted efficiently. Routine collection and testing of stool and sputum specimens of probable SARS case-patients may help the early detection of SARS-CoV infection.[1]

References

SARS-associated coronavirus transmission, United States. Isakbaeva, E.T., Khetsuriani, N., Beard, R.S., Peck, A., Erdman, D., Monroe, S.S., Tong, S., Ksiazek, T.G., Lowther, S., Pandya-Smith, I., Anderson, L.J., Lingappa, J., Widdowson, M.A. Emerging Infect. Dis. (2004) [Pubmed]

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