The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Hym1p affects cell cycle progression in Saccharomyces cerevisiae.

The Saccharomyces cerevisiae HYM1 gene is conserved among eukaryotes. The mammalian orthologue (called MO25) mediates signaling through the AMP-activated protein kinase and other related kinases, implicated in cell proliferation. In yeast, Hym1p plays a role in cellular morphogenesis and also promotes the daughter cell-specific localization of the Ace2p transcription factor. Here, we report that increased dosage of HYM1 apparently shortens the G1 phase of the cell cycle. In the absence of HYM1 or ACE2, mother and daughter cells divide with the same generation times. Genetic analysis of HYM1, ACE2 and CLN3 mutants suggests that these genes together contribute to the establishment of asynchronous mother-daughter cell divisions, but probably not in a linear pathway. Our overall data suggest that Hym1p has a regulatory role in cell cycle progression.[1]

References

  1. Hym1p affects cell cycle progression in Saccharomyces cerevisiae. Bogomolnaya, L.M., Pathak, R., Guo, J., Cham, R., Aramayo, R., Polymenis, M. Curr. Genet. (2004) [Pubmed]
 
WikiGenes - Universities